Search Results - gregory+howard

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Reprogramming Aluminum Adjuvants to Tailor Immune Response

Unmet NeedVaccination is an important public health intervention that has led to the rapid decline of many infectious diseases. To maximize safety and minimize reactogenicity, vaccine development is gradually shifting from whole, inactivated vaccines to well defined subunit vaccines. However, this approach often suffers from reduced immunogenicity....

Published: 3/14/2025 | Inventor(s): Hai-Quan Mao, Gregory Howard

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases, Clinical and Disease Specializations > Immunology, Technology Classifications > Therapeutic Modalities > Vaccines

Polymeric Nanoparticle Compositions for Encapsulation and Sustained Release of Protein Therapeutics and Methods for Scalable Production of the Same

JHU Ref #: C14938Value Proposition· Biodegradable nanoparticle composition with core-shell structure· Controllable nanoparticle size with low polydispersity index· Wide range for protein loading level· Nanoparticles capable of sustained released over period of 2 weeks to 3 monthsUnmet Need· Protein therapeutics are used for...

Published: 3/13/2025 | Inventor(s): Hai-Quan Mao, Sashank Reddy, Xiyu Ke, Chenhu Qiu, Daniel Lucena Domingues, Gregory Howard

Keywords(s): Drug Delivery Vehicle, Drug Delivery Vehicle Synthesis Method, Nanoparticles, Therapeutic Matter, Therapeutics

Category(s): Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Therapeutic Modalities > Antibodies, Technology Classifications > Therapeutic Modalities > Dendrimers & Polymers