Search Results - chenhu+qiu

5 Results

Sort By:

Nanofiber Hydrogel Composite Gel to Prevent Scarring and Adhesion of Peripheral Nerves

JHU Ref #: [C17294] Value Proposition:· Application of composite hydrogel to mechanically irritated nerves can reduce perineural adhesions and scar formation.· Improves patient outcomes following peripheral nerve surgery. Technology Description· Researchers at Johns Hopkins have developed a nanofiber-hydrogel composite (NHC) material...

Published: 3/14/2025 | Inventor(s): Hai-Quan Mao, Sami Tuffaha, Sashank Reddy, Visakha Suresh, Thomas Harris, Chenhu Qiu

Keywords(s):

Category(s): Technology Classifications, Technology Classifications > Medical Devices > Plastic Surgery, Technology Classifications > Medical Devices > Regenerative Medicine, Technology Classifications > Medical Devices > Surgery, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Engineering Tech > Materials, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Therapeutic Modalities > Dendrimers & Polymers

Polymeric Nanoparticle Compositions for Encapsulation and Sustained Release of Neuromodulators

JHU Ref #: C16591Value Proposition· Protein delivery system with tunable, sustained release profile, high payload capacity, and bioactivity retention· Neurotoxin release profile of at least 120 days· Scalable and translational manufacturing processUnmet Need· Neurotoxins are widely used in the aesthetic and therapeutic space. Among...

Published: 3/14/2025 | Inventor(s): Hai-Quan Mao, Sashank Reddy, Chenhu Qiu

Keywords(s):

Category(s): Technology Classifications, Technology Classifications > Therapeutic Modalities

Nanoparticle Compositions for Sustained Delivery of Pro-regenerative Growth Factors for Nerve Repair, Preparation Processes of the Same, and Treatment Methods Using the Same

Unmet NeedGlobal incidence rates for peripheral nerve injury (PNI) are not well aggregated. However, US data collected shows that 20 million Americans suffer from peripheral nerve injury caused by trauma and medical disorders. [16] When a tension-free early repair is possible, microsurgical direct nerve repair with epineural sutures remains the gold...

Published: 3/14/2025 | Inventor(s): Hai-Quan Mao, Sami Tuffaha, Chenhu Qiu, Sashank Reddy, Yicheng Zhang, Thomas Harris, Philip Hanwright, Karim Sarhane, Nicholas von Guionneau, Erica Lee

Keywords(s):

Category(s): Clinical and Disease Specializations > Wound Healing, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms

BMETS Shared Decision Support Platform

Unmet NeedBone is the third most frequent site of tumor metastasis; it is estimated that 280,000 patients in the United States are living with symptomatic bone metastasis (SBM). Currently, physicians use their intuition and subjective experience with patients suffering from bone metastasis to make survival predictions that guide treatment decisions....

Published: 3/14/2025 | Inventor(s): Sara Alcorn, Jacob Fiksel, Scott Zeger, Theodore DeWeese, Thomas Smith, Todd Mcnutt, Jean Wright, Chen Hu, Lawrence Kleinberg, Christen Elledge

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Diagnostics > Prognostic Biomarkers

Polymeric Nanoparticle Compositions for Encapsulation and Sustained Release of Protein Therapeutics and Methods for Scalable Production of the Same

JHU Ref #: C14938Value Proposition· Biodegradable nanoparticle composition with core-shell structure· Controllable nanoparticle size with low polydispersity index· Wide range for protein loading level· Nanoparticles capable of sustained released over period of 2 weeks to 3 monthsUnmet Need· Protein therapeutics are used for...

Published: 3/13/2025 | Inventor(s): Hai-Quan Mao, Sashank Reddy, Xiyu Ke, Chenhu Qiu, Daniel Lucena Domingues, Gregory Howard

Keywords(s): Drug Delivery Vehicle, Drug Delivery Vehicle Synthesis Method, Nanoparticles, Therapeutic Matter, Therapeutics

Category(s): Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Therapeutic Modalities > Antibodies, Technology Classifications > Therapeutic Modalities > Dendrimers & Polymers