Search Results - karim+sarhane

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Nanoparticle Compositions for Sustained Delivery of Pro-regenerative Growth Factors for Nerve Repair, Preparation Processes of the Same, and Treatment Methods Using the Same

Unmet NeedGlobal incidence rates for peripheral nerve injury (PNI) are not well aggregated. However, US data collected shows that 20 million Americans suffer from peripheral nerve injury caused by trauma and medical disorders. [16] When a tension-free early repair is possible, microsurgical direct nerve repair with epineural sutures remains the gold...

Published: 6/28/2024 | Inventor(s): Hai-Quan Mao, Sami Tuffaha, Chenhu Qiu, Sashank Reddy, Yicheng Zhang, Thomas Harris, Philip Hanwright, Karim Sarhane, Nicholas von Guionneau, Erica Lee

Keywords(s):

Category(s): Clinical and Disease Specializations > Wound Healing, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms

Nanofiber wraps and sheaths to minimize inflammation and scarring

This invention describes a novel semi-permeable nanofiber construct in the form of a wrap or sheath that can prevent inflammatory scarring at primary nerve or vessel repair site. The wrap/sheath consists of a nanofiber mesh with thickness ranging from 50 to 500 m and pore size of less than 10 m, and can be used in the form of a sheet wrapping around...

Published: 6/27/2024 | Inventor(s): Zuhaib Ibrahim, Hai-Quan Mao, Kellin Krick, Russell Martin, Gerald Brandacher, Karim Sarhane

Keywords(s): Implanted Device, Implants, Therapeutic Devices, Therapeutics, Tissue Engineering/Regenerative Devices

Category(s): Technology Classifications > Medical Devices > Regenerative Medicine, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Therapeutic Modalities, Technology Classifications > Medical Devices