Search Results - j.+ippoliti

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Novel Oxazolidinone Antibacterials and the Synthetic Routes to Them

Marketing Summary Draft Novel Oxazolidinone Antibacterials and the Synthetic Routes to ThemJHU Ref #: C18144Value Proposition· Higher efficacy and lower toxicity oxazolidinone compounds· Positive activity demonstrated against M. abscessus· MIC values are the same or better than the current antibiotics in the market Unmet Need The...

Published: 3/14/2025 | Inventor(s): Gyanu Lamichhane, J. Ippoliti, Cole Friederichs, Connor Winkelhake, Ben Thompson, Kelsey Latterell

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Novel Oxazolidinones for Treatment of Bacterial Infections

Marketing Summary DraftNovel Oxazolidinones for Treatment of Bacterial InfectionsJHU Ref #: C14633Value Proposition· Belong to the same chemical family as Zyvox, marketed by Pfizer, but shows better efficacy· Positive activity demonstrated against M. tuberculosis· MIC values the same or better than the current antibiotics in the...

Published: 3/13/2025 | Inventor(s): Gyanu Lamichhane, J. Ippoliti

Keywords(s): Bacterial Infections, Disease Indication, Infectious Diseases, Novel, Predicted Novelty, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations, Technology Classifications > Therapeutic Modalities > Small Molecules, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Therapeutic Modalities, Clinical and Disease Specializations > Infectious Diseases > Bacterial Infections

An Oxazolidinone for Treatment of Infections with Mycobacterium Tuberculosis and Gram Positive Bacteria

TITLE: An Oxazolidinone for Treatment of Infections with Mycobacterium Tuberculosis and Gram Positive BacteriaCASE NUMBER: C13966UNMET NEEDTuberculosis (TB) is still one of the most difficult infectious diseases to treat, and the second most frequent cause of death due to infectious disease throughout the world. The number of cases of multidrug-resistant...

Published: 3/13/2025 | Inventor(s): Gyanu Lamichhane, J. Ippoliti

Keywords(s): Bacterial Infections, Disease Indication, Infectious Diseases, Novel, Predicted Novelty, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics, Tuberculosis, Tuberculosis (TB)

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Bacterial Infections, Clinical and Disease Specializations > Infectious Diseases > Tuberculosis, Technology Classifications > Therapeutic Modalities > Small Molecules, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Therapeutic Modalities