Search Results - tuberculosis

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Novel Molecular Method for the Detection of Mycobacterium Tuberculosis

Unmet NeedTuberculosis (TB) is a potentially serious infectious respiratory disease that is spread via coughs and sneezes. TB is one of the world’s deadliest diseases; one-fourth of the global population is currently infected with TB. In 2016 alone, 10.4 million people contracted TB with 1.7 million TB-related deaths. Lack of resources in developing...

Published: 6/27/2024 | Inventor(s): Pankaj Kumar, Gyanu Lamichhane

Keywords(s): Assay, Biomarker, Clinical Diagnostics, Diagnostic Biomarker, Disease Indication, In Vitro Diagnostics, Infectious Diseases, Tuberculosis

Category(s): Technology Classifications > Diagnostics > In Vitro Diagnostics, Clinical and Disease Specializations > Infectious Diseases, Clinical and Disease Specializations > Infectious Diseases > Tuberculosis, Clinical and Disease Specializations > Infectious Diseases > Bacterial Infections, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Research Tools > Assays

Clinical Decision Support MDR-TB Application

We have conceptualized and designed a clinical decision support application for MDR-TB. This application will assist clinicians (doctors, nurses, pharmacists) with the following types of information: a) standardized regimens; b) weight-based dosing; c) drug-drug interactions; d) side effect monitoring; e) symptom management; f) adherence to care.

Published: 6/27/2024 | Inventor(s): Jason Farley

Keywords(s): Bacterial Infections, Clinical Workflow Management System, Clinical Workflow Management Tools, Disease Indication, Healthcare Management, Infectious Diseases, Operations Management, Tuberculosis, Tuberculosis (TB)

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Bacterial Infections, Clinical and Disease Specializations > Infectious Diseases > Tuberculosis, Technology Classifications > Computers, Electronics & Software > Clinical Management, Technology Classifications > Computers, Electronics & Software > Healthcare IT, Technology Classifications > Computers, Electronics & Software, Clinical and Disease Specializations > Infectious Diseases

The Johns Hopkins MDR-TB Training Program

Technical DetailsJohns Hopkins Researchers have developed a program that focuses on principles of adult learning theory to include didactic sessions, large group case studies, case-based small group exercises, educational materials and clinical support documents. Sessions include power point slides with speaker notes. Paper-based clinical decision...

Published: 6/27/2024 | Inventor(s): Jason Farley

Keywords(s): Bacterial Infections, Disease Indication, Education Management, Healthcare Education, Infectious Diseases, Operations Management, Tuberculosis, Tuberculosis (TB)

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Bacterial Infections, Clinical and Disease Specializations > Infectious Diseases > Tuberculosis, Technology Classifications > Computers, Electronics & Software > Education Tech, Technology Classifications > Computers, Electronics & Software > Healthcare IT, Technology Classifications > Computers, Electronics & Software, Clinical and Disease Specializations > Infectious Diseases

TB-TLC = TB – Track/Link/Cure

We have designed a set of m-health applications that rapidly identify, link, and engage persons into TB care. Currently, reporting processes for TB are delayed and often require the healthcare worker to sift through multiple piles of paperwork. With this set of applications, a primary health care nurse or doctor can see the results in real-time directly...

Published: 6/27/2024 | Inventor(s): Jason Farley, Jane Mckenzie-White

Keywords(s): Bacterial Infections, Disease Indication, Disease Management System, Healthcare Management, Infectious Diseases, Operations Management, Tuberculosis, Tuberculosis (TB)

An Oxazolidinone for Treatment of Infections with Mycobacterium Tuberculosis and Gram Positive Bacteria

TITLE: An Oxazolidinone for Treatment of Infections with Mycobacterium Tuberculosis and Gram Positive BacteriaCASE NUMBER: C13966UNMET NEEDTuberculosis (TB) is still one of the most difficult infectious diseases to treat, and the second most frequent cause of death due to infectious disease throughout the world. The number of cases of multidrug-resistant...

Published: 6/27/2024 | Inventor(s): Gyanu Lamichhane, J. Ippoliti

Keywords(s): Bacterial Infections, Disease Indication, Infectious Diseases, Novel, Predicted Novelty, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics, Tuberculosis, Tuberculosis (TB)

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Bacterial Infections, Clinical and Disease Specializations > Infectious Diseases > Tuberculosis, Technology Classifications > Therapeutic Modalities > Small Molecules, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Therapeutic Modalities

Molecular Target of Mycobacterium Tuberculosis for Development of Drug and Vaccine

Susceptibility Target for TB TherapyJHU REF: C10895Invention novelty: This invention has identified a new target and a new way to kill the Mycobacterium tuberculosis pathogen.Value Proposition: Currently the mechanism by which M. tuberculosis maintains 3-3 cross-linkages in the peptidoglycan layer is not fully understood. Inventors at JHU and Universite...

Published: 6/27/2024 | Inventor(s): Jean-Luc Mainardi, Marie Lavollay, Michel Arthur, Radhika Gupta, Gyanu Lamichhane, William Bishai

Keywords(s): Bacterial Infections, Biomarker, Clinical Diagnostics, Disease Indication, In Vitro Diagnostics, Infectious Diseases, Mechanism-of-action Biomarker, Therapeutic Matter, Therapeutics, Tuberculosis, Tuberculosis (TB)

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Bacterial Infections, Clinical and Disease Specializations > Infectious Diseases > Tuberculosis, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Therapeutic Modalities > Targets, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Therapeutic Modalities

Auto-luminescent Mycobacterial Reporter Strains

C11128: Auto-luminescent Mycobacterial Reporter StrainsNovelty: This technology comprises novel engineered virulent strains of M. tuberculosis and M. ulcerans to produce light without requiring the addition of exogenous substrate.Value Proposition: The utility of existing bioluminescent mycobacterial strains in drug and vaccine development research...

Published: 6/27/2024 | Inventor(s): Eric Nuermberger, Jacques Grosset, Tianyu Zhang

Keywords(s): Bacterial Infections, Basic Research Biomarker, Discovery/Research Tools, Disease Indication, Infectious Diseases, Labels/Markers, Research Reagent, Tuberculosis, Tuberculosis (TB)

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Bacterial Infections, Clinical and Disease Specializations > Infectious Diseases > Tuberculosis, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Research Tools

Methionine Aminopeptidases from Mycobacterium Tuberculosis as Novel Antimycobacterial Targets: I. Cloning, Over-expression, and Purification of Methionine Aminopeptidases from Mycobacterium Tuberculosis. II. Discovery of Inhibitors of M. Tuberculos

C10796: Novel Antimycobacterial Targets Value Proposition: • Promising target for the development of new antibiotics. • Compounds that inhibit the growth of mycobacteria in culture. • Plasmids containing MetAP genes can be used to generate protein for anti-tuberculosis drug screening. Technical Details: Infectious diseases are the second...

Published: 6/27/2024 | Inventor(s): Jun Liu, Shridhar Bhat, Omonike Olaleye

Keywords(s): Antagonists/Inhibitors, Bacterial Infections, Discovery/Research Tools, Disease Indication, In Vitro Research Tool, Infectious Diseases, Non-novel, Off-the-shelf, Predicted Novelty, Small Molecules, Target-based Screening Tool, Therapeutic Matter, Therapeutic Substance, Therapeutics, Tuberculosis, Tuberculosis (TB)

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Bacterial Infections, Clinical and Disease Specializations > Infectious Diseases > Tuberculosis, Technology Classifications > Therapeutic Modalities > Small Molecules, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Therapeutic Modalities, Technology Classifications > Research Tools