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Methionine Aminopeptidases from Mycobacterium Tuberculosis as Novel Antimycobacterial Targets: I. Cloning, Over-expression, and Purification of Methionine Aminopeptidases from Mycobacterium Tuberculosis. II. Discovery of Inhibitors of M. Tuberculos

C10796: Novel Antimycobacterial Targets Value Proposition: • Promising target for the development of new antibiotics. • Compounds that inhibit the growth of mycobacteria in culture. • Plasmids containing MetAP genes can be used to generate protein for anti-tuberculosis drug screening. Technical Details: Infectious diseases are the second...

Published: 6/27/2024 | Inventor(s): Jun Liu, Shridhar Bhat, Omonike Olaleye

Keywords(s): Antagonists/Inhibitors, Bacterial Infections, Discovery/Research Tools, Disease Indication, In Vitro Research Tool, Infectious Diseases, Non-novel, Off-the-shelf, Predicted Novelty, Small Molecules, Target-based Screening Tool, Therapeutic Matter, Therapeutic Substance, Therapeutics, Tuberculosis, Tuberculosis (TB)

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Bacterial Infections, Clinical and Disease Specializations > Infectious Diseases > Tuberculosis, Technology Classifications > Therapeutic Modalities > Small Molecules, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Therapeutic Modalities, Technology Classifications > Research Tools