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SynGAP

C03367: SynGAP Technical Details: The PSD-95/SAP90 family of proteins have recently been implicated in the organization of synaptic structure. Here we describe the isolation of a novel ras-GTPase activating protein, GAPSYN, that specifically interacts with the PDZ domains of PSD-95 and SAP102 in vitro and in vivo. GAPSYN is selectively expressed...

Published: 6/26/2025 | Inventor(s): Richard Huganir, Jee-Hae Kim

Keywords(s): Cell Model, Cell Signaling, CNS and Neurological Disorders, Discovery/Research Tools, Disease Indication, In Vitro Research Tool, Molecular Switches/Receptors, Neurons, Research Reagent, Translational Research Biomarker

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Proteins, Ligands & Receptors, Technology Classifications > Research Tools