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Anthracycline doxorubicin-resistant carbonyl reductase-1 knock out mice

C04211: Anthracycline doxorubicin-resistant carbonyl reductase-1 knock out mice Technical Details: The cancer treatment drug doxorubicin (brand name adriamycin) is very effective against tumors, but causes a serious side effect of heart damage. This toxicity occurs in part because the enzyme carbonyl reductase metabolizes the drug into a cardiotoxic...

Published: 3/12/2026 | Inventor(s): Kathleen Gabrielson, Roger Reeves, Lisa Olson

Keywords(s): Basic Research Biomarker, Cancers, Discovery/Research Tools, Disease Indication, In Vivo Research Tool, Knock Out Mouse Model, Mouse Model

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools, Clinical and Disease Specializations > Oncology