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Search Results - oral+administration
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Antiviral Azide Containing Compounds
Unmet Need: Viral infections in humans, animals, plants and insects lead to many societal burdens including disease and agricultural loss. Most anti-viral treatment strategies to date are limited in scope to the virus of interest and often result in drug resistance, incomplete efficacy, and/or toxicity. Costs for viral specific targets can be massive...
Published: 3/13/2025
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Inventor(s):
Upinder Singh
,
Scott Grecian
,
Brian Agnew
,
David Graham
Keywords(s):
Antagonists/Inhibitors
,
Disease Indication
,
Drug Delivery Mechanism
,
Infectious Diseases
,
Oral Administration
,
Small Molecules
,
Therapeutic Matter
,
Therapeutic Substance
,
Therapeutics
Category(s):
Clinical and Disease Specializations
,
Clinical and Disease Specializations > Infectious Diseases
,
Technology Classifications > Therapeutic Modalities > Small Molecules
,
Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms
,
Technology Classifications > Therapeutic Modalities
Lipid Nanoparticles as Oral Vehicles of Immunotherapy
Unmet NeedType 1 diabetes (T1D) affects 1.25 million Americans currently and by 2050, this number is expected to reach 5 million. Though a currently untreatable autoimmune disease, one of the more promising approaches has been a costimulatory blockade of malfunctioning immune cells via administration of CTLA4-Ig. However, its efficacy is impeded by...
Published: 3/14/2025
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Inventor(s):
Giorgio Raimondi
,
Julia Patrone
,
Xiomara Calderon-Colon
,
Olivia Tiburzi
Keywords(s):
Diabetes
,
Disease Indication
,
Drug Delivery Mechanism
,
Drug Delivery Vehicle
,
Immunotherapy
,
Metabolic Disorders
,
Nanoparticles
,
Oral Administration
,
Single
,
Therapeutic Matter
,
Therapeutics
,
Therapy Type
Category(s):
Clinical and Disease Specializations > Diabetes > Type 1 Diabetes
,
Clinical and Disease Specializations > Diabetes
,
Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms
Multi-epitope Fusion Antigen Vaccine for ETEC
Unmet Need: Enterotoxigenic Escherichia coli (ETEC) is the leading cause of diarrheal diseases worldwide but to date no effective vaccine exists due to the heterogeneity in ETEC strains. There is a need for a vaccine that elicits a broad yet productive immune response against multiple ETEC antigens to provide protection. Technical Details: Researchers...
Published: 3/13/2025
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Inventor(s):
Weiping Zhang
,
David Sack
Keywords(s):
Biologics
,
Disease Indication
,
Drug Delivery Mechanism
,
Immunotherapy
,
Infectious Diseases
,
Oral Administration
,
Protein
,
Single
,
Therapeutic Matter
,
Therapeutic Substance
,
Therapeutics
,
Therapy Type
,
Vaccine
Category(s):
Clinical and Disease Specializations
,
Clinical and Disease Specializations > Infectious Diseases
,
Technology Classifications > Therapeutic Modalities > Biologics
,
Technology Classifications > Therapeutic Modalities > Vaccines
,
Technology Classifications > Therapeutic Modalities > Immunotherapies
,
Technology Classifications > Therapeutic Modalities > Proteins
,
Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms
,
Technology Classifications > Therapeutic Modalities
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