Search Results - rebecca+schulman

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2D RNA Gradient Pattern Generation using Photopatterned Chemical Sources
Unmet Need: Living organisms detect and produce chemical gradients for a variety of different tasks, including morphogenesis, chemotaxis, and distributed computation. Synthetic chemical gradient generators have been developed to recreate the spatially heterogenous chemical environments seen in biological systems. Some previously developed methods for...
Published: 6/28/2024   |   Inventor(s): Moshe Rubanov, Rebecca Schulman
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Category(s): Technology Classifications > Research Tools
Aptamer Regulated Transcription for In-vitro Sensing and Transduction
Unmet Need: Biomarkers are an incredibly important tool for diagnosing everything from autoimmune diseases, cancer, and metabolic disorders to creating personalized medicine and recommendations for certain treatments such as transplants, chemotherapy, vaccination, etc. Currently, most protein biomarker detection is still done by conventional protein...
Published: 6/28/2024   |   Inventor(s): Heon Joon Lee, Rebecca Schulman, Samuel Schaffter
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Category(s):  
Growth and Site-specific Organization of Micro-scale Bimolecular Devices on Living Mammalian Cells
Unmet Need: One aspect of a cell’s function is its ability to form organized structures both within the cell and with its immediate surrounding environment. On cell surfaces, these nanostructures can serve as scaffolds or operate functionally to aid in cellular fate decisions, signal amplification and cellular cross-talk. There is a need to understand...
Published: 6/28/2024   |   Inventor(s): Rebecca Schulman, Sisi Jia, Siew Cheng Phua, Yuta Nihongaki, Yizeng Li, Michael Pacella, Yi Li, Abdul Majeed Mohammed, Sean Sun, Takanari Inoue
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Category(s): Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Proteins, Ligands & Receptors, Technology Classifications > Research Tools
Method to Form DNA Hydrogels and Shape Changing Devices
Unmet NeedSmart materials are designed materials with one or more properties that can be significantly changed by external stimuli. Materials and devices that can change shape are critical to the function of soft robots, programmable matter, and many smart therapeutics. However, current shape change materials cannot be changed without a specific chemical...
Published: 6/27/2024   |   Inventor(s): David Gracias, Thao Nguyen, ChangKyu Yoon, Rebecca Schulman, Angelo Cangialosi, Ruohong Shi
Keywords(s): Biopsy Tools, Clinical Diagnostics, Diagnostic Tool
Category(s): Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics
Method to form DNA hydrogels and shape changing devices and actuators
Unmet NeedMaterials and devices capable of changing their shape are critical to the function of soft robots, programmable matter, and smart therapeutics. Many ‘smart’ materials and devices feature a stimulus-responsive architecture that allows for the shrinking or swelling of designated regions under controlled conditions. These mechanical deformations...
Published: 6/27/2024   |   Inventor(s): Angelo Cangialosi, ChangKyu Yoon, Joshua Fern, Thao Nguyen, David Gracias, Rebecca Schulman
Keywords(s):  
Category(s): Technology Classifications > Medical Devices > Therapeutic Devices
DNA Oligonucleotide Buffers
Unmet Need: A topic of research interest in the near past has been utilizing DNA as data storage, process information, and even use DNA in logic circuits. However, these applications require precise control over the chemical process responsible for storing, accessing and deleting data. Since the rate of a chemical process is usually dependent on the...
Published: 6/27/2024   |   Inventor(s): Rebecca Schulman, Dominic Scalise, Samuel Schaffter
Keywords(s): Buffer Solution, Buffer/Media Solution, Discovery/Research Tools, Research Reagent
Category(s): Technology Classifications > Research Tools > Buffers & Media Solutions
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