Search Results - sean+sun

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Growth and Site-specific Organization of Micro-scale Bimolecular Devices on Living Mammalian Cells

Unmet Need: One aspect of a cell’s function is its ability to form organized structures both within the cell and with its immediate surrounding environment. On cell surfaces, these nanostructures can serve as scaffolds or operate functionally to aid in cellular fate decisions, signal amplification and cellular cross-talk. There is a need to understand...

Published: 6/28/2024 | Inventor(s): Rebecca Schulman, Sisi Jia, Siew Cheng Phua, Yuta Nihongaki, Yizeng Li, Michael Pacella, Yi Li, Abdul Majeed Mohammed, Sean Sun, Takanari Inoue

Keywords(s):

Category(s): Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Proteins, Ligands & Receptors, Technology Classifications > Research Tools

A Novel, Organ-On-A-Chip Device for Assessing Trans-epithelial Transport, and Uses Thereof

Unmet NeedThe current drug development process is expensive, laborious, and only about 1 in 10 drugs that enter clinical trials ultimately receive FDA approval. One important factor that drives this high failure rate and the high costs associated with drug development is that traditional cell culture and animal-based methods for drug testing do not...

Published: 6/27/2024 | Inventor(s): Sean Sun, Mohammad Ikbal Choudhury

Keywords(s): Discovery/Research Tools, In Vitro Research Tool

Category(s): Technology Classifications > Research Tools > Blood & Tissue Samples

A 34x208 Base Pair Repeat Array Containing the 601 Nucleosome Positioning Sequence

TITLE A 34x208 Base Pair Repeat Array Containing the 601 Nucleosome Positioning SequenceCASE NUMBERC12555ABSTRACTPrevious published work by Widom and colleagues showed that nucleosomes can be tightly positioned on DNA by the so-called "601" nucleosome positioning sequence. We have generated a...

Published: 6/27/2024 | Inventor(s): Sean Sun, Gregory Bowman

Keywords(s): Basic Research Biomarker, Cloning Reagents, Discovery/Research Tools, Plasmid, Research Reagent

Category(s): Technology Classifications > Research Tools > Vectors & Plasmids, Technology Classifications > Research Tools