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Dendrimer-conjugated GCPII Inhibitors to Delay Loss of Muscle Mass and Strength

Value Proposition· GCPII inhibitor has a low IC50 (<5 nM), suggesting greater potency and less systemic toxicity.· Functional improvements after treatment include 95% preservation of muscle mass, 96% preservation of grip strength, 25% greater isometric force.· Decreased decline in neuromuscular transmission compared to control. Technology...

Published: 3/13/2026 | Inventor(s): Barbara Slusher, Yu Su, Kannan Rangaramanujam

Keywords(s):

Category(s): Clinical and Disease Specializations > Musculoskeletal > Muscle Atrophy, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms

A Process for Making Iron Oxide Nanoparticle Preparations for Cancer Hyperthermia

C11199: Targeted radiation- and chemo-enhancing heat therapy for cancerNovelty: The proposed technology is a device and platform for treating local and metastatic cancer using multifunctionalized iron oxide nanoparticles in conjunction with radiation and chemotherapeutic agents.Value Proposition: Metastatic cancer is persistent and difficult to treat,...

Published: 3/12/2026 | Inventor(s): Zhigang Shen, Sung Lai Yun, Yit Wooi Goh, Meng Tack Ng, Robert Ivkov

Keywords(s): Cancers, Disease Indication, Drug Delivery Vehicle, Drug Delivery Vehicle Synthesis Method, Nanoparticles, Therapeutic Matter, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Therapeutic Modalities