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Personalized Care for Patients with Retinal Diseases

Unmet NeedAccording to the National Institute of Health, neovascular (wet) age-related macular degeneration (nAMD) is the most common cause of visual impairment among elderly patients in developed countries, and is predicted to increase globally from 196 million patients in 2020 to 288 million by 2040. Our current management of nAMD has two major limitations....

Published: 9/27/2024 | Inventor(s): Tin Yan Liu, Craig Jones

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Healthcare IT, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Computers, Electronics & Software > Machine Learning, Clinical and Disease Specializations > Ophthalmology > Age-Related Macular Degeneration

Augmented or Virtual Reality Based Evaluation of Visual Field

Sensitive visual field assessment using augmented realityJHU Ref #: C17601Unmet NeedWhile visual field measurement is key in diagnosing and monitoring eye and systemic diseases in patients (American Academy of Ophthalmology, 2022), current practices are either quick but imprecise (confrontation visual field tests that rely on the doctor’s hand gestures...

Published: 9/27/2024 | Inventor(s): Ali Saber Tehrani, Arash Saber Tehrani

Keywords(s):

Category(s): Clinical and Disease Specializations > Ophthalmology, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Machine Learning

Systems and Methods for Automatic Detection and Localization of Foreign Body Objects during (and after) Neurosurgery

Unmet Need· Retained foreign bodies (RFBs) are remnant materials following neurosurgery, often imperceptible cotton tufts, that can lead to neurological impairment and textilomas (Bechtold et al 2020). The incidence is estimated to be as high as 1 in 100 operations, and cost hospitals millions in healthcare costs and litigation (Whang et al....

Published: 9/27/2024 | Inventor(s): Amir Manbachi, Haley Abramson, Judy Huang, Henry Brem, Nicholas Theodore, George Coles

Keywords(s):

Category(s): Clinical and Disease Specializations > Neurology, Clinical and Disease Specializations > Surgery, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Research Tools > Surgical, Technology Classifications > Computers, Electronics & Software > Machine Learning

Three Material Decomposition using a Triple-Layer Flat-Panel Detector

Value Proposition:Method for direct, real-time visualization of bone, water, and iodine contrast agents.Allows for better visualization of moving structures; reduces imaging artifacts induced by motion (i.e. beating heart) Technology DescriptionResearchers at Johns Hopkins have developed a method for fast processing of data acquired using a triple-layer...

Published: 9/27/2024 | Inventor(s): Joseph Stayman, Jianan Gang, Xiao Jiang

Keywords(s):

Category(s): Technology Classifications > Medical Devices > Imaging, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Computers, Electronics & Software > Machine Learning

Antibody Structure Prediction from Pre-trained Language Model (IgFold)

Inventor(s): Jeffrey Ruffolo and Jeffrey Gray Unmet Need: Antibodies are able to bind a diverse set of antigens and have become critical therapeutics and diagnostic molecules. Antibody binding is facilitated by a set of six hypervariable loops that are diversified through genetic recombination and mutation. An accurate structural model of the hypervariable...

Published: 9/27/2024 | Inventor(s): Jeffrey Gray, Jeffrey Ruffolo

Keywords(s):

Category(s): Copyright, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Research Tools > Antibodies

Machine Learning Algorithm for Delirium Prediction in the Intensive Care Unit

Unmet NeedDelirium is a potentially preventable and often reversible disorder of impaired cognition. It is common in the intensive care unit (ICU), with an overall prevalence of 32.3%. However, the prevalence is dependent on the type of patients. For example, among ventilated burn patients, the prevalence is 77%, and among mechanically ventilated patients,...

Published: 9/27/2024 | Inventor(s): Robert Stevens, Kirby Gong, Akaash Sanyal, Joanna Guo, Ryan Lu, Teya Bergamaschi, Han Kim

Keywords(s):

Category(s): Clinical and Disease Specializations > Neurology > Dementia, Clinical and Disease Specializations > Neurology > Cognitive Impairment, Clinical and Disease Specializations > Neurology, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Diagnostics > Prognostic Biomarkers

A System for the Automated Classification of Disease Tissue in Molecular Imaging Studies utilizing Convolutional Neural Networks with User-Selectable Sensitivity and Specificity

Unmet NeedMedical imaging is an important diagnostic tool used for the detection of a wide array of clinical conditions. The application of Artificial Intelligence (AI) and Deep Learning (DL) is being developed to assist medical imaging professionals manage the ever-growing number of images which they must interpret in their research and clinical practice....

Published: 9/27/2024 | Inventor(s): Jeffrey Leal

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Healthcare IT, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Diagnostics, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Medical Devices > Imaging

CloneRetriever: An Automated Algorithm to Identify B-cell and T-cell Gene Rearrangements by Next-Generation Sequencing

Unmet NeedIn the U.S., there are an estimated 1,297,027 people living with blood cancers (leukemia, lymphoma or myeloma), with an additional 178,520 people expected to be diagnosed each year (see Leukemia & Lymphoma Society). Diagnostics tools that utilize next-generation sequencing (NGS) technologies are often performed to identify gene rearrangements...

Published: 9/27/2024 | Inventor(s): Rena Xian, Eitan Halper-Stromberg, Richard Ambinder

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Computers, Electronics & Software > Precision Medicine Tools, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > Prognostic Biomarkers

Automated Pipeline for Acute Stroke Segmentation in Brain MRIs

Unmet NeedAccording to the World Health Organization annually, 15 million people worldwide suffer a stroke. Of these, 5 million die and another 5 million are left permanently disabled, placing a burden on family and community. Within the United States more than 795,000 people suffer from a stroke every year with more than 131,000 of these resulting...

Published: 9/27/2024 | Inventor(s): Andreia Faria, Chin-Fu Liu

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Computers, Electronics & Software > Machine Learning

Quantitative Human Motion Analysis using Video-based Pose Estimation

Unmet NeedHuman gait analysis is now common in many fields of clinical and basic research, but gold standard approaches – e.g., three-dimensional motion capture, instrumented mats or footwear, and wearables – are often expensive, immobile, data-limited, and/or require specialized equipment or expertise for operation, furthermore limiting the access...

Published: 9/27/2024 | Inventor(s): Ryan Roemmich, Jan Stenum

Keywords(s):

Category(s): Clinical and Disease Specializations > Neurology > Multiple Sclerosis, Clinical and Disease Specializations > Neurology > Parkinson’s Disease, Clinical and Disease Specializations > Neurology > Stroke, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Diagnostics, Technology Classifications > Diagnostics > Diagnostic Imaging

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