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Real-Time Prediction of Cardiovascular Complications of COVID-19 Using Machine Learning and High-Dimensional Clinical Data

Value Proposition:· High accuracy in predicting both all-cause mortality/cardiac arrest and thromboembolic events in hospitalized COVID-19 patients, with clinically meaningful early warning times. · Real-time patient risk assessment based on clinical data, via a continuously updating risk score for an outcome within a specific timeframe....

Published: 9/12/2025 | Inventor(s): Natalia Trayanova, Ashish Doshi, Eric Sung, Allison Hays, Julie Shade

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases > Covid-19, Technology Classifications > Computers, Electronics & Software > Machine Learning

Accelerating Numerical Methods with AI-Based Surrogate Models

Value Proposition: Efficient modeling of dynamic phenomena with negligible error rates below 1% Reduced computational demand, not dependent on large datasets Utility across different domains and scalable to multiscale challenges Applicable to life sciences, material science, and engineering sectors Unmet Need: Accurate modeling of material...

Published: 9/12/2025 | Inventor(s): Somdatta Goswami, Wei Wang

Keywords(s):

AR CPR: Augmented Reality System to Improve Cardiopulmonary Resuscitation

Unmet NeedAccording to the Pearlman School of Medicine, pediatric in-hospital cardiac arrest (IHCA) occurs frequently and has a high mortality rate. Each year more than 15,000 children receive cardiopulmonary resuscitation (CPR) for cardiac arrest during hospitalization in the United States (Topjian, et al., 2021). As many as 80% to 90% survive the...

Published: 9/12/2025 | Inventor(s): Therese Canares, Justin Jeffers, Keith Kleinman, Blake Schreurs, James Dean, Brandon Scott

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Computers, Electronics & Software > Sensors, Clinical and Disease Specializations > Pediatrics, Clinical and Disease Specializations > Cardiovascular > Cardiac Arrest, Technology Classifications > Medical Devices > Cardiology

AI-Powered Brain Tumor Prognosis Tool Post-Surgery

Value Proposition: Combines MRI imaging and clinical variables for a comprehensive and accurate prediction of brain tumor outcomes and can automates complex analyses to save time for clinicians while supporting personalized patient counseling and optimized treatment strategies. Demonstrates proven accuracy through validation on 600 glioblastoma...

Published: 9/12/2025 | Inventor(s): Julian Gendreau, Yuncong Mao, Linda Tang, Melanie Alfonzo Horowitz, Saket Myneni, Jacob Gould, Karim Ahmed

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Oncology > Glioblastoma, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Computers, Electronics & Software > Precision Medicine Tools

Methods and formulations for engineered peptide conjugates for sustained intraocular drug delivery

Value Proposition· Reducing the number of daily eye drop doses required for therapeutic effect in the posterior chamber· Limited systemic absorption of medication delivered via topical eyedrops Unmet Need· The mainstay of medication delivery to the eye remains topical eye-drops. While intravitreal injections have been used to deliver...

Published: 9/12/2025 | Inventor(s): Laura Ensign, Tung Heng Hsueh, Renee Chou, Michael Cummings, Justin Hanes

Keywords(s):

Category(s): Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Therapeutic Modalities > Peptides, Technology Classifications > Computers, Electronics & Software > Machine Learning, Clinical and Disease Specializations > Ophthalmology

Material Defect Evolution Reconstruction by Assimilation of Elastodynamic Displacement Signatures

Value Proposition:· Non-Destructive 3D Characterization: The technology enables real-time, non-invasive monitoring of defect evolution in crystalline materials, providing high-resolution insights without altering or damaging the sample.· Spatio-Temporal Resolution: Captures defect dynamics at nanometer-scale spatial resolution and nanosecond-scale...

Published: 9/12/2025 | Inventor(s): Jaafar El-Awady, Tamer Zaki, Junjie Yang

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Sensors, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Engineering Tech > Industrial Manufacturing, Technology Classifications > Engineering Tech > Materials

COVID.AI: Intelligent COVID Radiological Assessment and Diagnostic System and Methods :IC-RADS

Inventor(s): Vishwa Sanjay Parekh, Michael A. Jacobs Unmet Need:The COVID-19 pandemic, caused by SARS-CoV-2, has resulted in more than 365,000 deaths in the United States and over 1.9 million deaths worldwide. Diagnosis of COVID-19 has been largely limited to molecular and serologic tests, which are not indicative of the severity nor the progression...

Published: 9/12/2025 | Inventor(s): Michael Jacobs, Vishwa Parekh

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases > Covid-19, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Diagnostics

Parameterized denoising network

Unmet NeedThere exists a wide array of strategies for noise reduction in x-ray computed tomography (CT), most of which provide sufficient efficacy in providing a more optimal output. However, current machine learning approaches are developed to provide a singular output of the best solution. This, however, is limiting as certain applications require...

Published: 9/12/2025 | Inventor(s): Joseph Stayman, Jianan Gang, Jeremias Sulam, Wenying Wang

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence

Developing the POTOMAC model: A Novel Prediction Model to Study the Impact of LymphOpenia kineTics on Survival Outcomes in Head and Neck Cancer via an Ensemble Tree-based MAChine Learning Approach

Survival Outcome Prediction Model for Lymphopenia in Head and Neck CancerJHU Ref #: [C17597]Unmet NeedLymphopenia, a disorder in which your blood doesn't have enough white blood cells, is a potential marker of survival outcomes for many solid tumors of the head and neck. Currently, researchers disagree on whether lymphopenia reflects the patient’s...

Published: 9/12/2025 | Inventor(s): Carmen Kut, Harry Quon

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology > Head & Neck Cancer, Technology Classifications > Computers, Electronics & Software > Precision Medicine Tools, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Computers, Electronics & Software > Algorithms, Clinical and Disease Specializations > Hematology

Personalized Care for Patients with Retinal Diseases

Unmet NeedAccording to the National Institute of Health, neovascular (wet) age-related macular degeneration (nAMD) is the most common cause of visual impairment among elderly patients in developed countries, and is predicted to increase globally from 196 million patients in 2020 to 288 million by 2040. Our current management of nAMD has two major limitations....

Published: 9/12/2025 | Inventor(s): Tin Yan Liu, Craig Jones

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Healthcare IT, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Computers, Electronics & Software > Machine Learning, Clinical and Disease Specializations > Ophthalmology > Age-Related Macular Degeneration

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