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OPtimal Target Identification via Modeling of Arrhythmogenesis

Unmet Need· Atrial fibrillation affects millions of patients worldwide, with the number expected to grow 2.5-fold in the next 40 years. (Boyle et al., 2016) Ablation of cardiac tissue around the pulmonary veins is a standard treatment, but fails 20-40% of the time in patients with a type of atrial fibrillation called persistent atrial fibrillation....

Published: 9/27/2024 | Inventor(s): Natalia Trayanova, Adityo Prakosa, Ryan Bradley, Eugene Kholmovski, Syed Yusuf Ali, Carolyna Yamamoto

Keywords(s):

Category(s): Clinical and Disease Specializations > Cardiovascular > Arrhythmias, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Computers, Electronics & Software > Precision Medicine Tools

CloneRetriever: An Automated Algorithm to Identify B-cell and T-cell Gene Rearrangements by Next-Generation Sequencing

Unmet NeedIn the U.S., there are an estimated 1,297,027 people living with blood cancers (leukemia, lymphoma or myeloma), with an additional 178,520 people expected to be diagnosed each year (see Leukemia & Lymphoma Society). Diagnostics tools that utilize next-generation sequencing (NGS) technologies are often performed to identify gene rearrangements...

Published: 9/27/2024 | Inventor(s): Rena Xian, Eitan Halper-Stromberg, Richard Ambinder

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Computers, Electronics & Software > Precision Medicine Tools, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > Prognostic Biomarkers

Software to Assess the Potential Accuracy of Radiation Planning Volumes in Head and Neck Cancer

Unmet NeedIn the United States, head and neck cancer represents 3% of all cancers, with approximately 66,000 individuals developing head and neck cancer annually (see uptodate.com). In the cases of localized head and neck cancer, radiation therapy provides improved outcome over surgery and is a preferred method of treatment. The success of radiation...

Published: 9/27/2024 | Inventor(s): Harry Quon, Carmen Kut, Junghoon Lee, Ferdinand Hui

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software, Technology Classifications > Computers, Electronics & Software > Precision Medicine Tools, Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Oncology > Head & Neck Cancer

Sleep 101 App

C13650 – Sleep 101 App In general, there is a significant knowledge gap in sleep disorder recognition among clinicians and health professions trainees. The wide-spread adoption of mobile applications in the medical field can help diminish this gap efficiently and effectively. This technology is a pair of mobile health applications aimed at educating...

Published: 9/26/2024 | Inventor(s): Charlene Gamaldo, Rachel Marie Salas, Peter Dziedzic, Anthony Kwan, Paula David, Luis Buenaver

Keywords(s): Clinical Diagnostics, CNS and Neurological Disorders, Diagnostic Tool, Disease Indication, Screening Questionnaire, Sleep Disorders

Category(s): Clinical and Disease Specializations, Technology Classifications > Computers, Electronics & Software > Precision Medicine Tools, Technology Classifications > Diagnostics, Technology Classifications > Computers, Electronics & Software, Clinical and Disease Specializations > Neurology, Clinical and Disease Specializations > Neurology > Sleep Disorders

Danger Assessment app for Young Women with OneLove Foundation

Unmet NeedAround 1 in 4 women experience severe intimate partner physical violence, sexual violence, and/or stalking. Many women cannot live their lives without fear of being attacked or stalked by an ex or are trapped in an abusive relationship. There is a need to help women understand and classify abusive relationships so that they can better address...

Published: 9/26/2024 | Inventor(s): James Case, Jacquelyn Campbell

Keywords(s): Clinical Diagnostics, Diagnostic Tool, Screening Questionnaire

Category(s): Technology Classifications > Computers, Electronics & Software > Precision Medicine Tools, Technology Classifications > Diagnostics, Technology Classifications > Computers, Electronics & Software

Compensating for Polarization Changes Introduced by Components with Retardation in Polarization Sensitive Retinal Scanning Systems

Unmet NeedThe most sensitive part of the human retina, the fovea, changes the polarization state of light when scanned with a low-power polarized beam of light. This produces a particular pattern which can be used for eye tracking or monitoring central fixation. The latter is useful in diagnosing strabismus (cross-sightedness) and amblyopia (“lazy eye”),...

Published: 9/27/2024 | Inventor(s): Boris Gramatikov, David Guyton

Keywords(s): Industrial Equipment, Industrial Manufacturing, Machine Tools, Manufacturing Method

Category(s): Technology Classifications > Computers, Electronics & Software > Precision Medicine Tools, Technology Classifications > Engineering Tech > Industrial Manufacturing, Technology Classifications > Medical Devices, Clinical and Disease Specializations > Ophthalmology

Screening Method to Identify Scleroderma Immune Responses with Anti-cancer Activity, and Induction of such Immune Responses for Cancer Therapy

Unmet NeedEpidemiological studies have shown that patients with scleroderma, a type of autoimmune rheumatic disease affecting the skin and connective tissues, have an increased risk of developing cancer relative to the general population. The exact etiology of scleroderma is still unknown. The Scleroderma Foundation estimates about 100,000 to 300,000...

Published: 9/26/2024 | Inventor(s): Ami Shah, Livia Casciola-Rosen, Antony Rosen, Takeru Igusa, Marikki Laiho

Keywords(s): Antibodies, Autoimmune Diseases, Biologics, Biomarker, Cancers, Clinical Diagnostics, Diagnostic Biomarker, Disease Indication, In Vitro Diagnostics, Inflammatory Disorders, Risk Stratification, Scleroderma, Skin Disorders, Skin Fibrosis, Therapeutic Matter, Therapeutic Substance, Therapeutics

The Physicians Hand

Unmet Need486,000 Americans seek treatment for moderate-to-severe burns each year in the United States. The size of a burn is a major factor in predicting survival and determines the precise volume of intravenous fluids required to resuscitate patients in the immediate time period of burn treatment. The current standard of care uses hand-held charts,...

Published: 9/26/2024 | Inventor(s): Harry Goldberg, Stephen Milner

Keywords(s): Clinical Diagnostics, Diagnostic Tool, Disease Indication, Screening Questionnaire, Traumatic Injury

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Traumatic Injury, Technology Classifications > Computers, Electronics & Software > Precision Medicine Tools, Technology Classifications > Diagnostics, Technology Classifications > Computers, Electronics & Software

Classification of a Population of Objects by Convolutional Dictionary Learning with Class Proportion Data

Unmet NeedWhite blood cells (WBCs) -- which consist of granulocytes, lymphocytes, and monocytes -- are essential to the body’s immune system. Deficiency in any type of WBC can lead to infection or inflammation, and knowledge of a patient's WBC count is essential for the diagnosis and treatment of a wide range of conditions, including leucopenia,...

Published: 9/26/2024 | Inventor(s): Rene Vidal, Florence Yellin, Benjamin Haeffele

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Computers, Electronics & Software > Precision Medicine Tools

Screening instrument (PraPlus)

C01662: Questionnaires Pra and PraPlus for Health Risk AssessmentNovelty: Questionnaires for the prediction of future requirement of health services of elders for early-stage crisis intervention.Value Proposition: Population ageing is accompanied by rising numbers of elderly people requiring intensive health care. Therefore, the here-presented 8-item...

Published: 9/26/2024 | Inventor(s): Charles (Chad) Boult

Keywords(s): Clinical Diagnostics, Diagnostic Tool, Screening Questionnaire

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