Search Results - richard+ambinder

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CloneRetriever: An Automated Algorithm to Identify B-cell and T-cell Gene Rearrangements by Next-Generation Sequencing

Unmet NeedIn the U.S., there are an estimated 1,297,027 people living with blood cancers (leukemia, lymphoma or myeloma), with an additional 178,520 people expected to be diagnosed each year (see Leukemia & Lymphoma Society). Diagnostics tools that utilize next-generation sequencing (NGS) technologies are often performed to identify gene rearrangements...

Published: 3/14/2025 | Inventor(s): Rena Xian, Eitan Halper-Stromberg, Richard Ambinder

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Computers, Electronics & Software > Precision Medicine Tools, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > Prognostic Biomarkers

JSC1

Technical Details: This primary effusion lymphoma (PEL) cell line was established from lymphomatous peritoneal effusion tumor cells that were anaplastic, large, and hematopoietic in appearance. The resultant cell line has a similar morphology, and phenotype with strong CD45 and CD71, partial CD20, and lambda light chain restriction by flow cytometry....

Published: 3/13/2025 | Inventor(s): Richard Ambinder

Keywords(s): Basic Research Biomarker, Cell Lines, Discovery/Research Tools, Disease Indication, Human Cell Lines, In Vitro Research Tool, Infectious Diseases

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Research Tools > Human Cell Lines, Technology Classifications > Research Tools > Viruses, Technology Classifications > Research Tools