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Hypoxia-inducible factor reporter cell lines
Unmet NeedLow oxygen levels are a characteristic of many types of solid tumors. High levels of HIF1α, the transcription factor responsible for energy utilization under hypoxic conditions, has been implicated in tumor growth and resistance, angiogenesis, and poor patient prognosis. For these reasons, HIF1α remains an attractive target for novel cancer...
Published: 6/20/2024
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Inventor(s):
Peter Espenshade
,
Wei Shao
Keywords(s):
Basic Research Biomarker
,
Cell Lines
,
Discovery/Research Tools
,
In Vitro Research Tool
,
Mouse Cell Lines
Category(s):
Technology Classifications > Research Tools > Cell Lines
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