Search Results - yu-min+chuang

3 Results

Sort By:

A Vaccine to Reduce Treatment Time for Tuberculosis

Unmet NeedTuberculosis (TB) is one of the leading causes of death globally. A vaccine to prevent TB has not been approved since the development of the BCG vaccine in the early 20th century. New treatment paradigms using small molecule antibiotics have led to cures in a large proportion of individuals with drug-susceptible TB. The course of treatment...

Published: 7/5/2024 | Inventor(s): Richard Markham, Petros Karakousis, Styliani Karanika, James Gordy, Yu-Min Chuang

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases > Tuberculosis, Technology Classifications > Therapeutic Modalities > Vaccines, Clinical and Disease Specializations > Infectious Diseases > Tuberculosis (TB)

Targeting of Stat-3 Signaling in the Hematopoietic System Evokes Multicomponent Therapeutic Antitumor Immunity

C04665: Targeting of Stat-3 Signaling in the Hematopoietic System Evokes Multicomponent Therapeutic Antitumor Immunity Technical Details: The immune system can act as an extrinsic suppressor of tumors. Therefore, tumor progression depends in part on mechanisms that down modulate intrinsic immune surveillance. Identifying these inhibitory pathways...

Published: 7/4/2024 | Inventor(s): Richard Jove, Hua Yu, Marcin Kortylewski, Drew Pardoll

Keywords(s): Biologics, Cancers, Combination, Disease Indication, Gene Therapy/ Immunotherapy, Protein, Single, Targeted Therapy, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities > Gene Therapies, Technology Classifications > Therapeutic Modalities > Immunotherapies, Technology Classifications > Therapeutic Modalities > Proteins, Technology Classifications > Therapeutic Modalities > Small Molecules, Technology Classifications > Therapeutic Modalities

Stat3 Antagonists and Their Uses as Vaccines Against Cancer

C04271: Stat3 Antagonists and Their Uses as Vaccines Against Cancer Technical Details: The present invention relates to methods for treating and/or preventing cancer. In particular the present invention relates to ex vivo immunotherapeutic methods. The methods comprise decreasing Stat3 (signal transducer and activator of transcription3) expression...

Published: 7/4/2024 | Inventor(s): Richard Jove, Hua Yu, Drew Pardoll

Keywords(s): Biologics, Cancers, Disease Indication, Immunotherapy, Single, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type, Vaccine

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Immunotherapies, Technology Classifications > Therapeutic Modalities > Vaccines