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Generation of Tetracycline-Regulatable Conditional AIMP2 (Aminoacyl-tRNA Synthetase Complex-interacting Multifunctional Protein 2) Transgenic Mice

Invention novelty: This tangible material is a transgenic mice model expressing AIMP2 (Aminoacyl-tRNA synthetase complex-interacting multifunctional protein 2), a protein strongly associated with pathogenesis of Parkinson’s disease (PD). Value Proposition: No animal models overexpressing human AIMP2 exist. These transgenic mice are tools that can facilitate...

Published: 6/12/2026 | Inventor(s): Lino Tessarollo, Valina Dawson, Yunjong Lee, Debbie Swing, Ted Dawson

Keywords(s): CNS and Neurological Disorders, Discovery/Research Tools, Disease Indication, In Vivo Research Tool, Mouse Model, Mouse Model Xenograft, Parkinson's Disease, Translational Research Biomarker

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology > Parkinson's Disease, Technology Classifications > Research Tools > Animal Models, Clinical and Disease Specializations > Neurology, Technology Classifications > Research Tools