Search Results - samuel+collins

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Adoptive Transfer of CD49a TRM Stop and Reverse Lung Fibrosis

Value Proposition:· Cellular therapy for the treatment of lung fibrosis with potential to stop and reverse underlying disease pathology.· Improved efficacy and accessibility compared to status-quo therapies.· Potential autologous therapy, as peripheral T cells can be used to induce this tissue resident memory subset.Technology Description....

Published: 5/10/2024 | Inventor(s): Maureen Horton, Jonathan Powell, Samuel Collins, Yee Chan Li

Keywords(s):

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Respiratory Diseases, Technology Classifications > Therapeutic Modalities > Cell Therapies

A p105-based NF-(kappa) B Super repressor

C04290: A p105-based NF-(kappa) B Super repressor Technical Details: Nuclear factor (NF)-kB is a family of transcription factors that regulate immune and inflammatory responses, programmed cell death (apoptosis), and developmental processes. In normal cells, NF-kB is latent, and is activated transiently by stimuli and stresses. However, under pathological...

Published: 5/9/2024 | Inventor(s): Li Lin

Keywords(s): Biologics, Cancers, Chemotherapy, Disease Indication, Nucleic Acid, Single, Skin Cancer, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Dermatology, Clinical and Disease Specializations > Oncology > Skin Cancer, Technology Classifications > Therapeutic Modalities > Gene Therapies, Technology Classifications > Therapeutic Modalities > Proteins, Technology Classifications > Therapeutic Modalities > Targets, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities