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Semi-hollow or Fully Trabecular Topology Optimized Total Joint Replacement Implants

Unmet NeedOver 2 million joint replacement surgeries are done per year in the United States. However, the biomechanic functionality of joint implants is often limited because of the large discrepancies between the native bone of the patient and the material and structural properties of the metallic implants. In addition to the material of the implant...

Published: 5/9/2024 | Inventor(s): Jarred Bressner, Mikhail Osanov, James Guest

Keywords(s):

Category(s): Clinical and Disease Specializations > Musculoskeletal, Clinical and Disease Specializations > Surgery, Technology Classifications > Medical Devices > Orthopedic Devices, Technology Classifications > Medical Devices > Prosthetics

Artifact Control and Miniaturization of the Safe DC Stimulator for Neural Prostheses

Safe DC Stimulator for Neural ProsthesesJHU Ref #: [C11822] Unmet NeedCurrently, neural prostheses are limited because they excite neurons but cannot efficiently inhibit them. Direct current (DC) can excite, inhibit, or control extracellular potential of target neurons, but DC stimulation is biologically unsafe. The current solution is to direct DC...

Published: 5/9/2024 | Inventor(s): Charles Della Santina, Gene Fridman

Keywords(s): CNS and Neurological Disorders, Disease Indication, Neuroprosthetic Sensing Algorithms, Neuroprosthetics, Prosthetics, Therapeutic Devices, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology, Technology Classifications > Medical Devices > Neurostimulation, Technology Classifications > Medical Devices > Prosthetics, Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Therapeutic Devices

Targeting Interleukin 17 and Senescent Cells for Treatment of the Foreign Body Response

Unmet Need13 million medical devices are implanted annually in the United States. Synthetic biomaterials are the building blocks of these implanted devices. Although biomaterials are selected for durability and minimal host immune response, all implanted biomaterials induce the foreign body response (FBR) to some degree, which creates a capsule of fibrous...

Published: 5/9/2024 | Inventor(s): Jennifer Elisseeff, Drew Pardoll, Franck Housseau, Liam Chung

Keywords(s): Antagonists/Inhibitors, Implants, Small Molecules, Target, Therapeutic Devices, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations > Traumatic Injury, Technology Classifications > Therapeutic Modalities > Targets, Technology Classifications > Medical Devices > Prosthetics

Depth Filter for Visual Prostheses

Unmet NeedGlobally, 733 million people are visually impaired. In the US the economic burden of eye disorders and vision loss is estimated to be over $100 Billion per year. Visual prosthesis devices are used to restore partial vision or improve vision. These devices operate based on neuronal electrical stimulation at different locations along the visual...

Published: 5/9/2024 | Inventor(s): Gislin Dagnelie, Arup Roy, Avraham Caspi, Greg Seifert, Paul Gibson

Keywords(s): Disease Indication, Eye Disorders, Imaging and Sensing Systems, In Vivo Medical Imaging, Integrated Imaging System, Prosthetic Device, Prosthetics, Therapeutic Devices, Therapeutics

Category(s): Clinical and Disease Specializations > Ophthalmology, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices > Prosthetics

Cyclodextrin-incorporated Collagen Membrane for Biomedical Uses

Unmet NeedCorneal lacerations are a common type of eye injury. These can occur in varying degrees of severity, and in many cases the wound is non-self-sealing. This type of injury requires significant intervention including sutures and, in some cases, many layers of grafts. During the course of treatment patients are required to wear bandages that can...

Published: 5/9/2024 | Inventor(s): Jennifer Elisseeff, Qiongyu Guo, Shoumyo Majumdar

Keywords(s): Drug Delivery Device, Implanted Device, Implants, Prosthetic Device, Prosthetics, Therapeutic Devices, Therapeutics

Category(s): Technology Classifications > Medical Devices > Prosthetics, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Medical Devices

Electrode Assemblies for Detecting Muscle Signals in a Prosthetic Liner

C12890 EMG Electrode Placement within Prosthetic Limb LinerInvention Novelty: A novel method of integrating the electromyogram (EMG) electrodes within the liner of the prosthetic limb to ascertain the user’s intention and improve flexibility of the prosthetic device.Value Proposition: There are an estimated 1.9 million amputees in the US, with...

Published: 5/9/2024 | Inventor(s): Nitish Thakor, Girish Singhal, Neha Malhotra, Rahul Kaliki

Keywords(s): Prosthetic Feedback Systems, Prosthetics, Therapeutic Devices, Therapeutics

Category(s): Technology Classifications > Medical Devices > Prosthetics, Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Therapeutic Devices

Middle Ear Implant Sensor

C12346: Middle Ear Implant SensorNovelty: A piezoelectric sensor for monitoring compressive load and verifying proper sound conduction in middle ear implants to provide surgeons with real-time feedback regarding implant fit and positioning during surgery.Value Proposition: According to the World Health Organization, global incidence of middle ear-related...

Published: 5/9/2024 | Inventor(s): David Kitchin, Dawnielle Farrar-Gaines, George Coles, Howard Francis, Ioan Lina

Keywords(s): Disease Indication, Ear and Hearing Disorders, Prosthetic Feedback Systems, Prosthetics, Therapeutic Devices, Therapeutics

Category(s): Technology Classifications > Medical Devices > Prosthetics, Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Therapeutic Devices, Clinical and Disease Specializations > Ear, Nose & Throat > Hearing Disorders

A High-voltage CMOS Neuroelectronic Interface for a Multichannel Vestibular Prosthesis

C11184: Neuroelectronic Interface for a Multichannel Vestibular ProsthesisNovelty: The current invention is a vestibular prosthesis using a neuroelectronic interface to allow normal balance and head rotation sensation in patients suffering abnormal vestibular function.Value Proposition: In normal individuals, sensory organs within the inner ear modulate...

Published: 5/9/2024 | Inventor(s): Julius Georgiou, Zaven Kalayjian, Bryce Chiang, Gene Fridman, Andreas Andreou, Charles Della Santina

Keywords(s): CNS and Neurological Disorders, Disease Indication, Ear and Hearing Disorders, Hearing Disorders, Neuroprosthetics, Prosthetics, Therapeutic Devices, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Ear, Nose & Throat > Hearing Disorders, Clinical and Disease Specializations > Neurology, Technology Classifications > Medical Devices > Neurostimulation, Technology Classifications > Medical Devices > Prosthetics, Clinical and Disease Specializations > Ear, Nose & Throat, Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Therapeutic Devices

Vertebral Body Reduction Instrument

C10608: Vertebral Body Reduction InstrumentValue Proposition: Within the system, each module has two degrees of freedom (DOF) with uncoupled orthogonal translations. These uncoupled orthogonal translations allow for distraction/compression and translation of the vertebral bodies to be achieved over a defined spinal segment. Uncoupling of this action...

Published: 5/9/2024 | Inventor(s): Dan Stoianovici, Jean-Paul Wolinsky

Keywords(s): Prosthetic Device, Prosthetics, Therapeutic Devices, Therapeutics

Category(s): Technology Classifications > Medical Devices > Prosthetics, Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Therapeutic Devices