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A Multi-modal Deep Learning Method for Ventricular Arrhythmia Risk Stratification

Unmet NeedHypertrophic cardiomyopathy (HCM) is a rare genetic condition (prevalence in adults: 0.2-0.5%) that causes pathologic enlargement of the left ventricle (1). While many HCM patients live normal lives, some are at risk for severe cardiac complications, including sudden cardiac death due to ventricular arrhythmia (VA). VA risk is currently evaluated...

Published: 6/28/2024 | Inventor(s): Natalia Trayanova, Minglang Yin, Changxin Lai

Keywords(s):

Arrhythmic Sudden Death Survival Prediction using Deep Learning Analysis of Scarring in the Heart

Unmet Need:Sudden cardiac death (SCD) is a leading cause of death in western countries, accounting for 15 – 20% of deaths (Kumar, et al. 2021). Currently, the standard for estimating risk for SCD is based on a left ventricular ejection fraction (LVEF) lower than 30-35% (Russo et al, 2013) which captures only 20% of arrhythmic sudden cardiac deaths (SCDA)...

Published: 6/28/2024 | Inventor(s): Natalia Trayanova, Dan Popescu, Mauro Maggioni, Julie Shade

Keywords(s):

Category(s): Clinical and Disease Specializations > Cardiovascular, Clinical and Disease Specializations > Cardiovascular > Arrhythmia, Clinical and Disease Specializations > Cardiovascular > Arrhythmias, Clinical and Disease Specializations > Cardiovascular > Cardiac Arrest, Clinical and Disease Specializations > Cardiovascular > Ventricular Tachycardia, Clinical and Disease Specializations > Cardiovascular > Ventricular Fibrillation, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Computers, Electronics & Software > Machine Learning

An Intraprocedural Automatic Arrhythmia Origin Localization (AAOL) System

Unmet NeedAbnormal cardiac rhythms are often fatal. Specifically, ventricular arrhythmias, caused by abnormal electrical signals in the ventricles, cause 75 to 80% of sudden cardiac deaths every year. To prevent abnormal electrical activity in patients with various idiopathic ventricular tachycardias (IVA), radiofrequency intracardiac catheter ablation...

Published: 6/28/2024 | Inventor(s): Natalia Trayanova, Shijie Zhou, Jonathan Chrispin, John Sapp, Amir AbdelWahab

Keywords(s):

Category(s): Clinical and Disease Specializations > Cardiovascular > Ventricular Tachycardia, Technology Classifications > Computers, Electronics & Software > Algorithms

Non-invasive Method to Localize Regions Susceptible to Reentry Using 3D Computational Modelling and Reentry Vulnerability Index Mapping

Unmet NeedLife threatening ventricular tachycardia (VT) is a precursor of sudden cardiac death. VT may occur in patients with weakened heart muscle such as in the case of myocardiopathy and/or chronic myocardial infarction (MI). Radiofrequency catheter ablation is applied to regions of conduction delay to treat and or prevent the recurrence of these...

Published: 6/28/2024 | Inventor(s): Natalia Trayanova, Ryan O'Hara, Ruben Coronel, Pouya Jelvehgaran

Keywords(s):

Category(s): Clinical and Disease Specializations > Cardiovascular > Myocardial Infarction, Clinical and Disease Specializations > Cardiovascular > Ventricular Tachycardia, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Computers, Electronics & Software > Clinical Management

Personalized Heart Modeling Using Intramyocardial Fat Deposition on Computed Tomography to Predict Ablation Targets

Unmet NeedVentricular tachycardia (VT) is a life-threatening arrhythmia that contributes significantly to the mortality and morbidity of cardiovascular patients. Catheter ablation of VTs can potentially be curative, but recurrence rates remain unacceptably high. Major technological advancements in VT ablation are often highly invasive, time-consuming,...

Published: 6/28/2024 | Inventor(s): Natalia Trayanova, Eric Sung, Adityo Prakosa, Shijie Zhou

Keywords(s):

Category(s): Clinical and Disease Specializations > Cardiovascular > Ventricular Tachycardia, Technology Classifications > Computers, Electronics & Software

A method for cardiac low-voltage defibrillation by converting cardiac fibrillation to cardiac tachycardia followed by termination of cardiac tachycardia

C12013: Method for Cardiac Low-Voltage Defibrillation Value Proposition: Defibrillation by strong electric shock remains the only clinically proven method to terminate ventricular fibrillation (VF) and to prevent sudden cardiac death. The defibrillation of atrial fibrillation (AF) on the other hand is hindered by the possibility of inducing a rapid...

Published: 6/27/2024 | Inventor(s): Lukas Rantner, Natalia Trayanova

Keywords(s): Atrial Fibrillation (AF), Cardiovascular Diseases, Computer Systems Based on Specific Computational Models, Computing; Calculating; Counting, Disease Indication, Heart Stimulation, Interventional and Surgical Systems, Physics, Surgical Intervention Method, Ventricular Fibrillation, Ventricular Tachycardia

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular > Ventricular Fibrillation, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Medical Devices, Technology Classifications > Therapeutic Modalities, Clinical and Disease Specializations > Cardiovascular, Clinical and Disease Specializations > Cardiovascular > Atrial Fibrillation, Technology Classifications > Medical Devices > Cardiology, Clinical and Disease Specializations > Cardiovascular > Ventricular Tachycardia

Creation of non-invasive voltage maps prior to catheter ablation of VT

C11400: Non-invasive and Pre-Procedural Method to Create Cardiac Voltage MapNovelty: Pre-procedural and no-invasive method to create endocardial voltage map for catheter ablation procedure of ventricular tachycardia (VT)Value Proposition: Current method to create endocardinal voltage map for catheter ablation is invasive, time-consuming, and inaccurate....

Published: 6/27/2024 | Inventor(s): Christopher Miller, Takeshi Sasaki, Saman Nazarian

Keywords(s): Cardiovascular Diseases, Disease Indication, Interventional and Surgical Systems, Surgical Navigation, Ventricular Tachycardia

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular > Ventricular Tachycardia, Technology Classifications > Medical Devices > Surgical, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Medical Devices