Search Results - clinical+and+disease+specializations+%3e+oncology+%3e+lung+cancer

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Combination Small Molecule-Chemotherapy for Targeting of Cancer Stem Cells in Drug-resistant Lung Cancer

Value Proposition:· Combination treatment strategy enhances existing chemotherapy treatment regimens to improve long-term survival.· Integration of small molecules with conventional chemotherapy regimens establishes new treatment options for drug-resistant and recurrent lung cancer.· Cancer stem cells (CSCs) are a target in other...

Published: 3/14/2025 | Inventor(s): Mohammad Hoque, Pritam Sadhukhan

Keywords(s):

Category(s): Technology Classifications > Therapeutic Modalities > Small Molecules, Clinical and Disease Specializations > Oncology > Lung Cancer, Clinical and Disease Specializations > Oncology > Adenocarcinoma

Method to Enhance Pulmonary Dendritic Cell-mediated DNA Vaccination

Unmet NeedWith lung diseases, namely influenza and lung cancer, on the rise, pulmonary vaccination is a promising approach to elicit strong immunity to inhaled pathogens and lung cancer compared to systemic immunization strategies. In particular, inhaled DNA vaccination, a rapidly developing field, can potentially promote humoral and cellular immunity...

Published: 3/14/2025 | Inventor(s): Jung Soo Suk, Yoo Chun Kim, Justin Hanes

Keywords(s): Biologics, Cancers, Disease Indication, Drug Delivery Vehicle, Immunotherapy, Infectious Diseases, Influenza, Lung Cancer, Nanoparticles, Single, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type, Tuberculosis (TB), Vaccine

Category(s): Clinical and Disease Specializations > Infectious Diseases > Tuberculosis (TB), Clinical and Disease Specializations > Infectious Diseases > Influenza, Clinical and Disease Specializations > Immunology, Clinical and Disease Specializations > Immuno-Oncology, Clinical and Disease Specializations > Oncology > Lung Cancer, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Therapeutic Modalities > Vaccines

Low Dose Adjuvant Epigenetic Modifiers Inhibit Cancer Lung Metastases through Disruption of the Myeloid Environment in Pre-metastatic Niches

Unmet NeedCancer recurrence, even following complete surgical resection, remains a large unmet clinical problem. In non-small cell lung cancer (NSCLC) patients, recurrence following surgery remains 30-70%, and the five-year survival rate remains 23% with over 140,000 deaths occurring each year. Recurrence post-surgery can be driven by a number of factors,...

Published: 3/14/2025 | Inventor(s): Malcolm Brock, Zhihao Lu

Keywords(s): Antagonists/Inhibitors, Cancers, Chemotherapy/Chemotherapy, Combination, Disease Indication, Non-novel, Predicted Novelty, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type

Category(s): Clinical and Disease Specializations > Oncology > Lung Cancer, Technology Classifications > Therapeutic Modalities > Small Molecules

Lung Nodule Malignancy Risk Calculator

Unmet NeedLung cancer is a type of cancer that affects lung tissues and is categorized by the presence of abnormal cell division and rapid growth of lung tissue. Globally, lung cancer is a leading cause of cancer death and poses a major therapeutic burden with poor survival rates. According to estimates from the American Cancer Society, lung cancer...

Published: 3/14/2025 | Inventor(s): Peng Huang, Yuliang Li, Stephen Lam

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Healthcare IT, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology > Lung Cancer

PEGylated Human Heavy Chain Ferritin Nanocages and Their Uses for Therapeutic and Diagnostic Delivery

Unmet Need:Localized delivery of chemotherapeutics to the lung via inhalation provides a straightforward method of directly targeting lung cancers. However, due to the presence of multiple delivery barriers, the effectiveness of the approach has been limited. Here, we disclose an invention of a novel inhalable drug delivery platform capable of...

Published: 3/13/2025 | Inventor(s): Justin Hanes, Jung Soo Suk, Xinglu Huang

Keywords(s): Cancers, Disease Indication, Drug Delivery Vehicle, Lung Cancer, Nanoparticles, Therapeutic Matter, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology > Lung Cancer, Clinical and Disease Specializations > Respiratory Diseases, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities

Glioblastoma Biomarker for Improved Survival Prediction

TITLE: Glioblastoma Biomarker for Improved Survival PredictionCASE NUMBER: C13155UNMET NEEDGlioblastoma GBM), the most common primary brain tumor, has few available therapies providing significant improvement in survival. The median survival of patients after treatment is ~15 months, with only 3-5% surviving longer than 3 years. However, survival varies...

Published: 3/13/2025 | Inventor(s): Patrick Ha, Michael Lim, Chetan Bettegowda, Taeyoung Hwang, Chul-Kee Park, Dimitrios Mathios

Keywords(s): Biomarker, Brain Cancer, Breast Cancer, Cancers, Cervical Cancer, Clinical Diagnostics, Disease Indication, Glioma, In Vitro Diagnostics, Lung Cancer, Prognostic Biomarker

Non-ionizing, Non-invasive, Non-contact, and Real-time Tumor Detection Using Ultra-WideBand (UWB) Radar

C12383: Tumor Detection Using Radar-based Medical ImagingNovelty: A novel tumor-detection technique using Ultra-Wideband (UWB) radar.Value Proposition: UWB is a new technology used in military and commercial remote sensing applications for through-the-wall imaging, identifying hidden features obstructed by walls, concrete, or ground surfaces. This invention...

Published: 3/13/2025 | Inventor(s): Eun Oh, Yeonju Han-Oh

Keywords(s): Cancers, Disease Indication, Imaging and Sensing Systems, Imaging Modality, In Vivo Medical Imaging, Integrated Imaging System, Lung Cancer, Ultra-wide Band Radar (UWB)

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology > Lung Cancer, Clinical and Disease Specializations > Respiratory Diseases, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices, Clinical and Disease Specializations > Oncology

Molecular Characteristics of Non-small Cell Lung Cancer

C03957: Molecular Characteristics of Non-small Cell Lung Cancer Technical Details: We used hierarchical clustering to examine gene expression profiles generated by serial analysis of gene expression (SAGE) in a total of nine normal lung epithelial cells and non-small cell lung cancers (NSCLC). Separation of normal and tumor samples, as well as...

Published: 3/13/2025 | Inventor(s): David Sidransky, Mariana Nacht, Stephen Madden, Tatiana Dracheva, Jen Jin

Keywords(s): Biomarker, Cancers, Clinical Diagnostics, Diagnostic Biomarker, Disease Indication, In Vitro Diagnostics, Lung Cancer

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology > Lung Cancer, Clinical and Disease Specializations > Respiratory Diseases, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Oncology