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Search Results - john+laterra
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Method for highly efficient conversion of human stem cells to lineage-specific neurons.
Conversion of human stem cells to dopaminergic neurons using a single, high-efficiency factor JHU REF: [C12596] Invention novelty: To convert human stem cells into dopaminergic neurons at high efficiency. Value Proposition As many as one million Americans suffer from Parkinson's disease (Parkinson’s Disease Foundation, 2012). Cell...
Published: 3/13/2025
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Inventor(s):
John Laterra
,
Mingyao Ying
Keywords(s):
Basic Research Biomarker
,
Cell Lines
,
Cell Model
,
Clinical Diagnostics
,
CNS and Neurological Disorders
,
Discovery/Research Tools
,
Disease Indication
,
Human Cell Lines
,
In Vitro Diagnostics
,
In Vitro Research Tool
,
Sample Prep Method
,
Stem Cells
,
Therapeutic Matter
,
Therapeutic Substance Synthesis Method
,
Therapeutics
,
Translational Research Biomarker
Category(s):
Technology Classifications > Research Tools > Cell Lines
,
Technology Classifications > Research Tools > Stem Cells
,
Technology Classifications > Therapeutic Modalities
,
Technology Classifications > Research Tools
,
Technology Classifications > Research Tools > Human Cell Lines
,
Clinical and Disease Specializations > Neurology > Neurodegeneration
,
Technology Classifications > Diagnostics > Biomarkers
Highly Efficient Conversion of Human Stem Cells to Dopaminergic Neurons by Proneural Transcription Factor Atoh1
C11838: Novel Method to Convert Human Stem Cells into Dopaminergic NeuronsNovelty: This technology is a novel approach to induce and drive a highly efficient conversion of human neural stem cells (NSCs) into dopaminergic (DA) neurons.Value Proposition: Cell replacement therapy is a potential strategy to counter progressive neurological diseases, such...
Published: 3/13/2025
|
Inventor(s):
Mingyao Ying
,
John Laterra
Keywords(s):
Cell Model
,
CNS and Neurological Disorders
,
Discovery/Research Tools
,
Disease Indication
,
In Vitro Research Tool
,
Stem Cells
,
Translational Research Biomarker
Category(s):
Technology Classifications > Research Tools > Cell Lines
,
Technology Classifications > Research Tools > Stem Cells
,
Technology Classifications > Research Tools
,
Clinical and Disease Specializations > Neurology
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