🔍
Search Results - dimpy+kalia
3
Results
Sort By:
Published Date
Updated Date
Title
ID
Descending
Ascending
Rufinamide derivatives as novel drugs against epilepsy syndromes caused by aberrant sodium channel behavior
Unmet NeedLennox-Gastaut Syndrome (LGS) is rare and severe form of childhood-onset epilepsy associated with various types of seizures and cognitive dysfunction that persist into adulthood; yet, to date, LGS management is challenged by the lack of reliable diagnostic tests and potentially grave side-effects of available therapeutics. Rufinamide is a...
Published: 3/13/2025
|
Inventor(s):
Frank Bosmans
,
Dimpy Kalia
Keywords(s):
Antagonists/Inhibitors
,
CNS and Neurological Disorders
,
Disease Indication
,
Epilepsy
,
Genetic Disorders
,
Novel
,
Predicted Novelty
,
Small Molecules
,
Therapeutic Matter
,
Therapeutic Substance
,
Therapeutics
Category(s):
Clinical and Disease Specializations
,
Technology Classifications > Therapeutic Modalities > Small Molecules
,
Clinical and Disease Specializations > Neurology
,
Technology Classifications > Therapeutic Modalities
,
Clinical and Disease Specializations > Neurology > Epilepsy
,
Clinical and Disease Specializations > Rare Diseases
Novel Triazole Compounds to Treat Nav1.6-related Brain Disorders
Unmet NeedAbnormal behavior of sodium (Nav) channels is linked to a variety of epilepsy syndromes, movement disorders, and neuropathic pain. While researchers continue to elucidate the roles of different Nav channel isoforms within a variety of neurological disorders, current therapeutics influence numerous Nav channel isoforms, resulting in off-target...
Published: 3/13/2025
|
Inventor(s):
Frank Bosmans
,
Dimpy Kalia
Keywords(s):
Antagonists/Inhibitors
,
CNS and Neurological Disorders
,
Disease Indication
,
Epilepsy
,
Neuropathy
,
Non-novel
,
Novel
,
Off-the-shelf
,
Predicted Novelty
,
Small Molecules
,
Therapeutic Matter
,
Therapeutic Substance
,
Therapeutics
Category(s):
Clinical and Disease Specializations
,
Clinical and Disease Specializations > Neurology
,
Technology Classifications > Therapeutic Modalities > Small Molecules
,
Technology Classifications > Therapeutic Modalities
,
Clinical and Disease Specializations > Neurology > Neuropathy
,
Clinical and Disease Specializations > Neurology > Epilepsy
Johns Hopkins University PROTEIN-DB2 Database System
C04853: Johns Hopkins University PROTEIN-DB2 Database SystemNovelty: The current invention is a relational database for proteomic experiments.Value Proposition: Proteomic data collection follows complex workflow, ranging from gel electrophoresis to mass spectrometry to liquid chromatography or a combination thereof. In addition, amplification of low-abundance...
Published: 3/13/2025
|
Inventor(s):
Raimond Winslow
,
Stephen Granite
,
Chunguang Yang
,
Ali Ali
,
Donita Robinson
Keywords(s):
Computer and Network Systems
,
Computer Software
,
Computing; Calculating; Counting
,
Data Processing Systems or Methods, Specifically Adapted fo~
,
Data Processing Systems or Methods, Specifically Adapted for
,
Physics
Category(s):
Technology Classifications > Computers, Electronics & Software > Financial Tech
,
Technology Classifications > Computers, Electronics & Software
,
Technology Classifications > Computers, Electronics & Software > Databases
JHTV Home
|
Search
|
Login/Subscribe
2017 - 2022 © Johns Hopkins Technology Ventures. All Rights Reserved. Powered by
Inteum