Search Results - neuropathy

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Novel Triazole Compounds to Treat Nav1.6-related Brain Disorders

Unmet NeedAbnormal behavior of sodium (Nav) channels is linked to a variety of epilepsy syndromes, movement disorders, and neuropathic pain. While researchers continue to elucidate the roles of different Nav channel isoforms within a variety of neurological disorders, current therapeutics influence numerous Nav channel isoforms, resulting in off-target...

Published: 3/13/2025 | Inventor(s): Frank Bosmans, Dimpy Kalia

Keywords(s): Antagonists/Inhibitors, CNS and Neurological Disorders, Disease Indication, Epilepsy, Neuropathy, Non-novel, Novel, Off-the-shelf, Predicted Novelty, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology, Technology Classifications > Therapeutic Modalities > Small Molecules, Technology Classifications > Therapeutic Modalities, Clinical and Disease Specializations > Neurology > Neuropathy, Clinical and Disease Specializations > Neurology > Epilepsy

Pirt-GCaMP3 Mice

Invention novelty: Primary sensory neurons in the DRG play essential role in initiating somatosensory such as pain, itch, and touch by directly sensing various sensory stimuli like mechanical, chemical, and thermal stimuli. Dysfunction of these neurons often leads to various pathological conditions including chronic pain and itch. Currently, no one...

Published: 3/13/2025 | Inventor(s): Xinzhong Dong

Keywords(s): Basic Research Biomarker, CNS and Neurological Disorders, Discovery/Research Tools, Disease Indication, In Vivo Research Tool, Itch, Knock In Mouse Model, Mouse Model, Neuropathy

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools, Clinical and Disease Specializations > Neurology > Itch, Clinical and Disease Specializations > Neurology > Neuropathy

Ethoxyquin and Derivatives for Treatment of Peripheral Neuropathies and Other Neurodegenerative Disorders

Peripheral neuropathies are a group of neurodegenerative disorders affecting the peripheral nerves. Currently there is no effective therapy that prevents nerve degeneration except in cases of autoimmune peripheral neuropathies. Wehave now identified a compound, ethoxyquin (EQ), that prevents nerve degeneration in chemotherapy-induced peripheral neuropathy...

Published: 3/13/2025 | Inventor(s): Weiran Chen, Jing Zhu, Ahmet Hoke

Keywords(s): CNS and Neurological Disorders, Disease Indication, Neuropathy, Non-novel, Off-the-shelf, Predicted Novelty, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology > Neuropathy, Technology Classifications > Therapeutic Modalities > Small Molecules, Clinical and Disease Specializations > Neurology, Technology Classifications > Therapeutic Modalities

Medical Device for Treatment of Ulnar Neuropathy

C04545: Medical Device for Treatment of Ulnar Neuropathy Value Proposition: Key Benefits • Stand alone device for treating ulnar neuropathy • Affordable • Safe • Easy to wearTechnical Details: UlnarGuardTM is a non-invasive medical device used for treating pain and disability due to ulnar neuropathy. It is designed to worn under clothing so that...

Published: 3/13/2025 | Inventor(s): Justin Mcarthur, Beth Hogans

Keywords(s): CNS and Neurological Disorders, Disease Indication, Neuropathy, Orthotic Device, Orthotics, Therapeutic Devices, Therapeutics, Ulnar Neuropathy

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology > Neuropathy, Clinical and Disease Specializations > Neurology > Ulnar Neuropathy, Technology Classifications > Medical Devices > Orthopedic Devices, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Medical Devices, Clinical and Disease Specializations > Neurology