Search Results - harry+larman

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Value Proposition· Target associated with viral load reduction identified from a large pool of study participants who had low level viremia· Potential to reduce disease severity in at-risk populations· Proactive approach to lower viral load in individuals who could become infected Unmet NeedHuman immunodeficiency virus (HIV) impacts millions...

Published: 6/27/2025 | Inventor(s): Susan Eshleman, Harry Larman, Kai Kammers, Oliver Laeyendecker, Wendy Grant-McAuley

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases > HIV, Clinical and Disease Specializations > Infectious Diseases > HIV/AIDS, Technology Classifications > Therapeutic Modalities > Antibodies, Technology Classifications > Therapeutic Modalities > Therapeutic Antibodies

An Efficient Phage Display Based Protease Activity Profiling Platform

Unmet NeedProtein cleavage, catalyzed by enzymes (proteases) that break peptide bonds, is a fundamental molecular process essential to cellular viability and tissue physiology across all kingdoms of life. Protein cleavage plays pivotal roles in tissue remodeling and morphogenesis, infection, blood coagulation, neoplasia, and cancer metastasis. The enzymatic...

Published: 6/27/2025 | Inventor(s): Harry Larman, Gabriel Roman-Melendez, Thiagarajan Venkataraman

Keywords(s): Assay, Cancers, Clinical Diagnostics, Discovery/Research Tools, Disease Indication, In Vitro Diagnostics (Old), In Vitro Research Tool, Research Reagent, Viruses

Category(s): Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Immuno-Oncology, Technology Classifications > Research Tools > Assays, Technology Classifications > Research Tools > Viruses, Technology Classifications > Diagnostics > In Vitro Diagnostics

HIV Serosignatures for Cross-sectional Incidence Estimation

Unmet NeedAccording to UNAIDS, there were approximately 36.9 million people worldwide living with HIV/AIDS in 2017. An estimated 1.8 million individuals worldwide became newly infected with HIV in 2017 – about 5,000 new infections per day.Measuring the incidence of HIV in a population is important for improving at-risk populations and intervention...

Published: 6/27/2025 | Inventor(s): Susan Eshleman, Oliver Laeyendecker, Harry Larman, Kai Kammers

Keywords(s): Clinical Diagnostics, Diagnostic Tool, Disease Indication, HIV/AIDS, Infectious Diseases, Measurement Tool

Category(s): Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > Prognostic Biomarkers