Search Results - harry+larman

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Value Proposition· Target associated with viral load reduction identified from a large pool of study participants who had low level viremia· Potential to reduce disease severity in at-risk populations· Proactive approach to lower viral load in individuals who could become infected Unmet NeedHuman immunodeficiency virus (HIV) impacts millions...

Published: 3/14/2025 | Inventor(s): Susan Eshleman, Harry Larman, Kai Kammers, Oliver Laeyendecker, Wendy Grant-McAuley

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases > HIV, Clinical and Disease Specializations > Infectious Diseases > HIV/AIDS, Technology Classifications > Therapeutic Modalities > Antibodies, Technology Classifications > Therapeutic Modalities > Therapeutic Antibodies

An Efficient Phage Display Based Protease Activity Profiling Platform

Unmet NeedProtein cleavage is a fundamental molecular process, essential to cellular viability and tissue physiology across all kingdoms of life. Human proteases comprise a diverse set of enzymes with at least 569 members, making up five distinct catalytic classes. Cancer associated protease activities are often dysregulated and usually contribute to...

Published: 3/14/2025 | Inventor(s): Harry Larman, Gabriel Roman-Melendez, Thiagarajan Venkataraman

Keywords(s): Assay, Cancers, Clinical Diagnostics, Discovery/Research Tools, Disease Indication, In Vitro Diagnostics (Old), In Vitro Research Tool, Research Reagent, Viruses

Category(s): Clinical and Disease Specializations > Oncology, Clinical and Disease Specializations > Immuno-Oncology, Technology Classifications > Research Tools > Assays, Technology Classifications > Research Tools > Viruses, Technology Classifications > Diagnostics > In Vitro Diagnostics

HIV Serosignatures for Cross-sectional Incidence Estimation

Unmet NeedAccording to UNAIDS, there were approximately 36.9 million people worldwide living with HIV/AIDS in 2017. An estimated 1.8 million individuals worldwide became newly infected with HIV in 2017 – about 5,000 new infections per day.Measuring the incidence of HIV in a population is important for improving at-risk populations and intervention...

Published: 3/14/2025 | Inventor(s): Susan Eshleman, Oliver Laeyendecker, Harry Larman, Kai Kammers

Keywords(s): Clinical Diagnostics, Diagnostic Tool, Disease Indication, HIV/AIDS, Infectious Diseases, Measurement Tool

Category(s): Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > Prognostic Biomarkers