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Chemically-induced Mutations of Sema3a, Sec24b, and Megf8 in Mouse

Value Proposition· Novel loss-of-function mutations: Three distinct ENU-induced point mutations (Sema3A^K108N, Sec24b^Y613X, and Megf8^L1775P) that create specific loss-of-function phenotypes while maintaining protein expression and secretion· Validated genetic models: Each strain has been thoroughly characterized and phenotypically validated...

Published: 10/23/2025 | Inventor(s): Janna Merte, David Ginty

Keywords(s): Basic Research Biomarker, Discovery/Research Tools, In Vivo Research Tool, Mouse Model, Mouse Model Xenograft

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools