Search Results - david+ginty

13 Results

Sort By:

023046 B6.129S6(Cg)-Ntrk2tm2.1Ddg; 025417 STOCK Megf8tm1.2Ddg; 025418 C3;B6-Megf8m687Ddg; 025615 STOCK Islr2tm2.1Ddg; 027214 B6.129S6(Cg)-Ntrk2tm3.1(cre/ERT2)Ddg

MUTATIONS OF Ntrk2, Megf8 and Islr2 IN MOUSE MODELSJHU REF: C13722Invention novelty: This tangible material includes a mutant strain of mice produced by inducing chemical mutations of Ntrk2, Megf8 and Islr2 mutations in mouse models. Value Proposition023046 B6.129S6(Cg)-Ntrk2tm2.1Ddg/J 025417 STOCK Megf8tm1.2Ddg/J 025418 C3;B6-Megf8m687Ddg/J 025615...

Published: 6/27/2024 | Inventor(s): David Ginty

Keywords(s): Basic Research Biomarker, Discovery/Research Tools, In Vivo Research Tool, Knock Out Mouse Model, Mouse Model

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools

Chemically-induced Mutations of Sema3a, Sec24b, and Megf8 in Mouse

MUTATIONS OF SEMA3A, SEC24B, AND MEGF8 IN MOUSE MODELSJHU REF: C12484 Invention novelty: This tangible material includes a mutant strain of mice produced by inducing chemical mutations of SEMA3A, SEC24B and MEGf8 mutations in mouse models. Value PropositionSema3a point mutant miceSec24b point mutant mice Megf8L1775P point mutant mouseTechnical DetailsJohns...

Published: 6/27/2024 | Inventor(s): Janna Merte, David Ginty

Keywords(s): Basic Research Biomarker, Discovery/Research Tools, In Vivo Research Tool, Mouse Model, Mouse Model Xenograft

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools

Targeted Gfp Knock-in to the Islr2 (aka Linx) Locus

Linx Null Mouse ModelsJHU REF: C12483Invention novelty: This tangible material includes linx (Islr2) null mouse strain generated by the knock-in of targeted Gfp in the linx locus. Value Proposition:Linx mutant mouse strain.Technical Details:Johns Hopkins researchers have developed a linx null mouse strain. This was done in order to assess the in vivo...

Published: 6/27/2024 | Inventor(s): Kenji Mandai, David Ginty

Keywords(s): Cell Model, CNS and Neurological Disorders, Discovery/Research Tools, Disease Indication, In Vitro Research Tool, In Vivo Research Tool, Knock In Mouse Model, Mouse Model, Neurons, Translational Research Biomarker

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Animal Models

Chemically-induced Mutations of B3gnt1 and Ispd in Mouse

MUTANT MOUSE MODELS FOR NEURODEVELOPMENTAL RESEARCH JHU REF: C12482Invention novelty: This tangible material includes mouse models with mutant B3gnt1 and Ispd genes.Value PropositionMouse strains with chemically-induced mutations of B3gnt1 and Ispd genes.Technical DetailsJohns Hopkins researchers have developed chemically altered mouse strain with mutations...

Published: 6/27/2024 | Inventor(s): Kevin Wright, David Ginty

Keywords(s): Basic Research Biomarker, Discovery/Research Tools, In Vivo Research Tool, Knock Out Mouse Model, Mouse Model, Mouse Model Xenograft

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools

Congenic, targeted mutant mouse line B6.129S6(Cg)-Ntrk1 ::superscript-tm2Ddg::/J (aka B6.Cg-Ntrk1::superscript-tm2DdG::/J)

C11345: Mouse strain for studying TrkA in neurons.Mice is stored at The Jackson Laboratory (www.jax.org)Jax Stock No. 013720 B6.l29S6(Cg)-Ntrkltm2Ddg/J Technical Details: Mouse models can make essential contributions to our understanding of the cause, prevention and treatment of disease. Inventor has disclosed a knock-in mutant mouse line that expresses...

Published: 6/27/2024 | Inventor(s): David Ginty

Keywords(s): Basic Research Biomarker, Cell Lines, Discovery/Research Tools, In Vitro Research Tool, Mouse Cell Lines

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools

Chemically-induced mutant mouse line C3.B6-Erbb3::superscript-m3329Ddg::/J (aka C3.B6-Erbb3::superscript-I449S::/DdgJ )

C11344: Mouse strain with Erbb3 mutation to study nervous system development.Mice is stored at The Jackson Laboratory (www.jax.org)Jax Stock No. 013059 - C3.B6.-Erbb3tm33292Ddg/J Technical Details: Erbb3 encodes a protein that belongs to the Epidermal Growth Factor Receptor (EGFR) family of receptor tyrosine kinases. ERBB3 is known to interact with...

Published: 6/27/2024 | Inventor(s): David Ginty

Keywords(s): Basic Research Biomarker, Cell Lines, CNS and Neurological Disorders, Discovery/Research Tools, Disease Indication, In Vitro Research Tool, In Vivo Research Tool, Mouse Cell Lines, Mouse Model

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools, Clinical and Disease Specializations > Neurology

TrkB(f/f) Mouse

C11277: Mouse line with a TrkB mutation with Lox P sites.Value Proposition: Mouse lines can make essential contributions to our understanding of the cause, prevention and treatment of various diseases and conditions. This invention provides a mouse line harboring a TrkB mutation with Lox P sites useful for Cre-mediated recombination to generate a null...

Published: 6/27/2024 | Inventor(s): David Ginty

Keywords(s): Basic Research Biomarker, Discovery/Research Tools, In Vivo Research Tool, Mouse Model, Mouse Model Xenograft

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools

TrkB-F616A

C11240: Mouse line with mutation in TrkB receptor. Value Proposition: The TrkB receptor is part of the large family of receptor tyrosine kinases. The present technology is a mouse line harboring a Phenylalanine to Alanine mutation in the TrkB receptor at F616 without Lox P sites. STOCK Ntrk2tm1Ddg/J Strain #:022363

Published: 6/27/2024 | Inventor(s): David Ginty

Keywords(s): Basic Research Biomarker, Discovery/Research Tools, In Vivo Research Tool, Knock In Mouse Model, Mouse Model

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools

Polyclonal Antisera Specific for Neuropilin-1 and Polyclonal Antisera Specific for Neuropilin-2

C10703: Polyclonal Antibodies for Neuropilin-1 (Npn-1) and Polyclonal Antibodies for Neuropilin-2 (Npn-2)Value Proposition: These are rabbit polyclonal antibodies directed against the rodent proteins neuropilin-1 and neuropilin-2. The neuropilins are semaphorin receptors.Technical Details: The semaphorin family contains a large number of phylogenetically...

Published: 6/27/2024 | Inventor(s): David Ginty, Alex Kolodkin

Keywords(s): Antibodies, Basic Research Biomarker, Discovery/Research Tools, Polyclonal Antibodies, Proteomics/Immunoassays, Proteomics/Immunoassays Antibodies, Research Reagent

Category(s): Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Assays, Technology Classifications > Research Tools

Floxed Ret Mouse

C10009: Floxed Ret Mouse Technical Details: Scientists at JHU have created a mouse that harbors mutations allowing for the conditional inactivation of the Ret protein through the use of Cre mouse lines. Looking for Partners: These mouse lines can be used to investigate the role of GDNF in neural cell development and survival and may help to...

Published: 6/27/2024 | Inventor(s): David Ginty, Ted Dawson, Joseph Savitt

Keywords(s): Basic Research Biomarker, Discovery/Research Tools, In Vivo Research Tool, Knock In Mouse Model, Mouse Model

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools

1 2