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Chemically-induced Mutations of B3gnt1 and Ispd in Mouse

Value Proposition· Human disease relevance: Recapitulate key dystroglycanopathy features including cobblestone lissencephaly, neuronal migration defects, and muscular dystrophy· Complementary severity spectrum: B3gnt1 mutants survive to adulthood with mild symptoms; Crppa mutants show severe early phenotypes· Drug discovery ready: Enable...

Published: 10/9/2025 | Inventor(s): Kevin Wright, David Ginty

Keywords(s): Basic Research Biomarker, Discovery/Research Tools, In Vivo Research Tool, Knock Out Mouse Model, Mouse Model, Mouse Model Xenograft

Category(s): Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools