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Artificial Lymph Nodes for T cell Immunotherapy
Unmet Need Adoptive T cell transfer immunotherapy is a promising approach for treating a variety of cancer tumors. They involve the removal, culture, and expansion of resident T cells ex-vivo several thousand fold before reinfusion back into the body. However, a concern with current culturing methods is their inconsistency in developing and retaining...
Published: 3/13/2025
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Inventor(s):
Jonathan Schneck
,
John Hickey
,
Hai-Quan Mao
Keywords(s):
Cancer Cells
,
Cancers
,
Cell Model
,
Discovery/Research Tools
,
Disease Indication
,
Immunotherapy
,
In Vitro Research Tool
,
Single
,
Therapeutic Matter
,
Therapeutic Method
,
Therapeutics
,
Therapy Type
Category(s):
Clinical and Disease Specializations > Immuno-Oncology
Cationic Biodegradable Polymer Compositions of Biomimetic Particles including Artificial Antigen Presenting Cells
Unmet NeedOver the past decade, a myriad of immune cell therapies based on the infusion of allogeneic immune cells into patients have been tested and progressed in clinical applications. Despite continual advances, immune cell therapy via antigen presenting cells is relatively expensive and time consuming, so biomimetic materials have been applied to...
Published: 3/13/2025
|
Inventor(s):
Jordan Green
,
Jonathan Schneck
,
Alyssa Kosmides Galaro
,
Randall Meyer
,
John Hickey
,
Kelly Rhodes
Keywords(s):
Autoimmune Diseases
,
Biologics
,
Cancers
,
Disease Indication
,
Drug Delivery Vehicle
,
Inflammatory Disorders
,
Polymers
,
Therapeutic Matter
,
Therapeutic Substance
,
Therapeutics
,
Whole cell
Category(s):
Technology Classifications > Therapeutic Modalities > Cell Therapies
,
Technology Classifications > Medical Devices > Regenerative Medicine
,
Technology Classifications > Therapeutic Modalities > Immunotherapies
,
Clinical and Disease Specializations > Immuno-Oncology
,
Clinical and Disease Specializations > Autoimmunity
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