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An Adduct-specific Anti-thymidylate Synthase Antibody for Monitoring Fluorouracil Anticancer Therapy

TITLEAn Adduct-specific Anti-thymidylate Synthase Antibody for Monitoring Fluorouracil Anticancer TherapyCASE NUMBERC11954ABSTRACTWe developed a functional assay for a class of widely used anti-cancer drugs, 5-fluorouracil and related compounds (SFU). It is well established that SFU works largely by inhibiting the enzyme thymidylate synthase (TS) in...

Published: 3/13/2025 | Inventor(s): Kalpeshkumar Patel, Scott Kern

Keywords(s): Antibodies, Biomarker, Cancers, Clinical Diagnostics, Discovery/Research Tools, Disease Indication, In Vitro Diagnostics, Monoclonal Antibodies, Pharmakodynamic Biomarker, Research Reagent

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Research Tools > Antibodies, Technology Classifications > Diagnostics, Technology Classifications > Research Tools