Search Results - kuangwen+hsieh

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Quantitative Measurements of 16S rRNA from Single Bacterial Cells for Accelerated Pathogen Identification and Antimicrobial Susceptibility Testing

Unmet needUrinary tract infection (UTI) is one of the most common infectious diseases in the world, affecting 50-60% of women at least once in their lifetime. In the United States, UTIs account for over 2 million emergency department visits and approximately $3.5 billion in healthcare costs annually. Unfortunately, UTI resistance to first line antibiotics...

Published: 6/28/2024 | Inventor(s): Tza-Huei Wang, Aniruddha Kaushik, Kuangwen Hsieh

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases > Antimicrobial Resistance

Impedance Based Feedback Control of Microfluidic Valves

Unmet NeedDroplet microfluidics is a growing field due to its potential to create high throughput assays while reducing reagent consumption in the process. The technology creates small droplets within fluid channels to generate biological assays. Frequently, these assays require an injection step so as to merge a reagent with the droplet at the correct...

Published: 6/27/2024 | Inventor(s): Tza-Huei Wang, Brant Axt, Yi-Fan Hsieh, Kuangwen Hsieh, Helena Zec, Aniruddha Kaushik, Yue Yun

Keywords(s): Computer and Network Systems, Computer Software, Discovery/Research Tools, Research Reagent

Category(s): Technology Classifications > Computers, Electronics & Software, Technology Classifications > Research Tools

Multiplexed, Continuous-Flow, Droplet-Based Platform for High-Throughput Genetic Detection

Unmet NeedMaintaining levels of crop production has become increasingly critical amidst growing populations and other emerging challenges for the $300 billion global crop market. Traditional crossbreeding of plants for desirable phenotypic traits is being improved by genetic marker assisted selection (MAS), where known genetic markers associated with...

Published: 6/27/2024 | Inventor(s): Tza-Huei Wang, Kuangwen Hsieh, Helena Zec, Lingshu Liu, Aniruddha Kaushik, Yue Yun

Keywords(s): Assay, Clinical Diagnostics, Crop Management, In Vitro Diagnostics, Microfluidic, Operations Management

Category(s): Technology Classifications > Industrial Tech > Agriculture, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Research Tools > Assays, Technology Classifications > Research Tools > Microfluidics, Technology Classifications > Diagnostics, Technology Classifications > Industrial Tech, Technology Classifications > Research Tools, Technology Classifications > Engineering Tech > Agriculture

Streamlined Platform for Bacterial Identification and Antimicrobial Susceptibility Test

Unmet NeedFor managing dangerous infections, clinicians need to know what bacteria strain(s) is/are causing the infections, the bacterial loads, and the antibiotic resistance profile of the bacteria. Without knowing this vital information in a timely manner, it is impossible to begin using narrow-spectrum antibiotics that can effectively treat the...

Published: 6/27/2024 | Inventor(s): Tza-Huei Wang, Pornpat Athamanolap, Liben Chen, Kuangwen Hsieh

Keywords(s): Assay, Bacterial Infections, Clinical Diagnostics, Diagnostic Tool, Disease Indication, In Vitro Diagnostics, Measurement Tool, Microfluidic

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Infectious Diseases > Bacterial Infections, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics > In Vivo Diagnostics, Technology Classifications > Research Tools > Assays, Technology Classifications > Research Tools > Microfluidics, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Research Tools