Search Results - liudmila+cebotaru

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Use of CFTR Modulators for the Treatment of ADPKD

Unmet Need: Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the progressive enlargement of multiple renal cysts, leading to chronic pain, hypertension, and decline in renal function and renal failure in a substantial subset of patients. Fluid enters the cysts via a cAMP-dependent process involving the cystic fibrosis transmembrane...

Published: 1/22/2026 | Inventor(s): Liudmila Cebotaru

Keywords(s): Biologics, Protein, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Proteins, Technology Classifications > Therapeutic Modalities

ABCA4 Cell Lines

TITLE: ABC4A cell linesCASE NUMBER: C13886ABSTRACTStargardt disease is the most common form of early onset macular degeneration. Mutations in ABCA4, a member of the ATP-binding cassette (ABC) family, are associated with Stargardt disease. JHU researchers have examined two disease-causing mutations in the NBD1 region of ABCA4, R1108C and...

Published: 1/22/2026 | Inventor(s): Liudmila Cebotaru

Keywords(s): Cell Lines, Discovery/Research Tools, Disease Indication, Eye Disorders, Human Cell Lines, In Vitro Research Tool, Macular Degeneration, Neurodegeneration

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology > Neurodegeneration, Clinical and Disease Specializations > Ophthalmology > Macular Degeneration, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Human Cell Lines, Clinical and Disease Specializations > Neurology, Clinical and Disease Specializations > Ophthalmology, Technology Classifications > Research Tools