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Hyaluronic Acid Binding Polymer System Transforms Tissue and Biomaterial Surfaces

We introduce a transformational biomaterial approach to engineering lubrication at the tissue surface that can be applied in a single application. Articular cartilage explants were modified with a synthetic peptide-polymer system designed to non-covalently bind HA to the tissue surface and work synergistically with HA in the local fluid environment....

Published: 6/27/2024 | Inventor(s): Michael Corvelli, Anirudha Singh, Shimon Unterman, Jennifer Elisseeff

Keywords(s): Drug Delivery Vehicle, Implanted Device, Implants, Therapeutic Devices, Therapeutic Matter, Therapeutics, Tissue Engineering/Regenerative Devices

Category(s): Technology Classifications > Medical Devices > Regenerative Medicine, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Therapeutic Modalities, Technology Classifications > Medical Devices