Search Results - shimon+unterman

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Hyaluronic Acid Binding Polymer System Transforms Tissue and Biomaterial Surfaces

We introduce a transformational biomaterial approach to engineering lubrication at the tissue surface that can be applied in a single application. Articular cartilage explants were modified with a synthetic peptide-polymer system designed to non-covalently bind HA to the tissue surface and work synergistically with HA in the local fluid environment....

Published: 6/27/2024 | Inventor(s): Michael Corvelli, Anirudha Singh, Shimon Unterman, Jennifer Elisseeff

Keywords(s): Drug Delivery Vehicle, Implanted Device, Implants, Therapeutic Devices, Therapeutic Matter, Therapeutics, Tissue Engineering/Regenerative Devices

Category(s): Technology Classifications > Medical Devices > Regenerative Medicine, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Therapeutic Modalities, Technology Classifications > Medical Devices

Modification of a Scaffold by Hyaluronic Acid Binding Peptide for Hyaluronic Acid Retention and Tissue Engineering Applications

C10108: Method for Improved Hyaluronic Acid Retention In VivoNovelty: This technology presents a novel use of hyaluronic acid- (HA) binding peptide to aid in the retention of HA at its injection site. This technology has applications in many areas of medicine.Value Proposition: HA is an important component of the extracellular matrix and is used in...

Published: 6/27/2024 | Inventor(s): Jennifer Elisseeff, (Hyeseung) Janice Lee (Logan), Shimon Unterman

Keywords(s): Buffer/Media Solution, Culture Media, Discovery/Research Tools, Research Reagent, Translational Research Biomarker

Category(s): Technology Classifications > Research Tools > Buffers & Media Solutions, Technology Classifications > Research Tools