Search Results - piotr+walczak

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Method for Reversible Blood-brain Barrier Opening Using Melittin and Melittin Variants

Unmet NeedThe blood-brain barrier (BBB) is responsible for regulating the brain microenvironment by tightly controlling the entry of molecules and cells into the brain. This restricted access has presented challenges in the delivery of therapeutic agents to the brain. As a result, only a few central nervous system disorders are currently treatable with...

Published: 6/12/2026 | Inventor(s): Peter Searson, Kalina Hristova, Raleigh Linville, Alexander Komin, Piotr Walczak

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Category(s): Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms

MRI-guided Blood Brain Barrier Disruption System for Drug Delivery

Unmet Need: The blood-brain barrier (BBB) is a major hurdle to therapeutic agents reaching the brain. Osmolar agents can be used to create openings in the BBB, but this technique is clinically limited because of wide variability in the size and location of the resulting openings. JHU inventors have developed a system and highly controlled procedure...

Published: 6/12/2026 | Inventor(s): Monica Pearl, Miroslaw Janowski, Piotr Walczak

Keywords(s): CNS and Neurological Disorders, Disease Indication, Integrated Imaging System, Interventional and Surgical Systems, Surgical Intervention Method, Surgical Navigation

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Neurology, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices > Surgical, Technology Classifications > Therapeutic Modalities, Technology Classifications > Diagnostics, Technology Classifications > Medical Devices