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Emission Ratiometric Kinase Activity Reports in High Throughput Drug Screening and Analysis

Unmet Need: Genetically-encoded reporters based on fluorescence resonance energy transfer (FRET) have become powerful tools for monitoring the activities of protein kinases and second messengers in live-cell imaging, but their application in high throughput assays has yet to be realized. Protein phosphorylation is one of the major regulatory mechanisms...

Published: 3/13/2025 | Inventor(s): Qiang Ni, Michael Allen, Jin Zhang

Keywords(s): Basic Research Biomarker, Discovery/Research Tools, Enzymes, Recombinant Proteins, Research Reagent

Category(s): Technology Classifications > Research Tools > Proteins, Ligands & Receptors, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Assays