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C10131: MKK4/MAP2K4 KO Lines for Drug DiscoveryValue Proposition: MKK4 (JNKK1, MAP2K4, and SEK1), a dual-specificity kinase gene on chromosome 17p11, is a tumor suppressor gene that is mutated in a subset of most tumor types. MKK4 protein is activated by several kinases, and active MKK4 cooperates with MKK7 to phosphorylate and thereby activate Jun...

Published: 3/13/2025 | Inventor(s): Steven Cunningham, Eike Gallmeier, Scott Kern

Keywords(s): Cancer Cells, Cancers, Cell Model, Discovery/Research Tools, Disease Indication, In Vitro Research Tool, Translational Research Biomarker

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools, Technology Classifications > Research Tools > Human Cell Lines