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MKK4/MAP2K4 KO Lines for Drug Discovery
C10131: MKK4/MAP2K4 KO Lines for Drug DiscoveryValue Proposition: MKK4 (JNKK1, MAP2K4, and SEK1), a dual-specificity kinase gene on chromosome 17p11, is a tumor suppressor gene that is mutated in a subset of most tumor types. MKK4 protein is activated by several kinases, and active MKK4 cooperates with MKK7 to phosphorylate and thereby activate Jun...
Published: 3/13/2025
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Inventor(s):
Steven Cunningham
,
Eike Gallmeier
,
Scott Kern
Keywords(s):
Cancer Cells
,
Cancers
,
Cell Model
,
Discovery/Research Tools
,
Disease Indication
,
In Vitro Research Tool
,
Translational Research Biomarker
Category(s):
Clinical and Disease Specializations
,
Clinical and Disease Specializations > Oncology
,
Technology Classifications > Research Tools > Cell Lines
,
Technology Classifications > Research Tools
,
Technology Classifications > Research Tools > Human Cell Lines
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