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Photoacoustic Imaging Platform for Intraoperative Evaluation and Treatment of Peripheral Nerve Injuries

Value Proposition:Highly accurate and objective determination of nerve injury site during surgical operations.Reduces patient risk during nerve surgeries by improving upon existing rudimentary methods.Quantifies nerve regeneration potential for a prognosis of patient recovery.Accessible and mobile imaging device for intraoperative use or postoperative...

Published: 9/12/2025 | Inventor(s): Muyinatu Bell, Michelle Graham, Nicholas von Guionneau, Sami Tuffaha

Keywords(s):

Category(s): Technology Classifications > Medical Devices > Imaging, Technology Classifications > Medical Devices > Surgical, Technology Classifications > Computers, Electronics & Software > Algorithms, Clinical and Disease Specializations > Traumatic Injury, Clinical and Disease Specializations > Surgery, Technology Classifications > Diagnostics > Prognostic Biomarkers

Predictive Algorithms for MISKD Clinical Decision Support System

Unmet NeedChildren hospitalized with SARS-Cov-2 infection are at risk for two similar inflammatory syndromes: Kawasaki disease (KD), and multi-system inflammatory syndrome in children (MIS-C). However, current clinical diagnostic standards for these two conditions have considerable overlap, which can lead to misdiagnosis and suboptimal treatment and...

Published: 9/12/2025 | Inventor(s): Cedric Manlhiot, Bhargava Kumar Chinni, Shelby Kutty

Keywords(s):

Category(s): Clinical and Disease Specializations, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Clinical and Disease Specializations > Infectious Diseases > Covid-19, Clinical and Disease Specializations > Inflammation

Accelerating Numerical Methods with AI-Based Surrogate Models

Value Proposition: Efficient modeling of dynamic phenomena with negligible error rates below 1% Reduced computational demand, not dependent on large datasets Utility across different domains and scalable to multiscale challenges Applicable to life sciences, material science, and engineering sectors Unmet Need: Accurate modeling of material...

Published: 9/12/2025 | Inventor(s): Somdatta Goswami, Wei Wang

Keywords(s):

Material Defect Evolution Reconstruction by Assimilation of Elastodynamic Displacement Signatures

Value Proposition:· Non-Destructive 3D Characterization: The technology enables real-time, non-invasive monitoring of defect evolution in crystalline materials, providing high-resolution insights without altering or damaging the sample.· Spatio-Temporal Resolution: Captures defect dynamics at nanometer-scale spatial resolution and nanosecond-scale...

Published: 9/12/2025 | Inventor(s): Jaafar El-Awady, Tamer Zaki, Junjie Yang

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Sensors, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Engineering Tech > Industrial Manufacturing, Technology Classifications > Engineering Tech > Materials

Software Tools for Tomographic Reconstruction

Value Proposition· Superior Image Quality – the proposed nonlinear DPS method outperforms traditional reconstruction methods and linear DPS models, offering better high-quality images across different acquisition protocols compared to conditionally trained deep learning approaches· State-of-the-Art Reconstruction – cutting-edge implementations...

Published: 9/12/2025 | Inventor(s): Joseph Stayman, Xiao Jiang, Shudong Li, Altea Lorenzon, Peiqing Teng

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis

A System and Method for Real-Time Ventricular Arrhythmia Localization and Catheter Navigation Using Surface ECG

Unmet NeedVentricular arrhythmias (VAs) are common arrhythmias associated with morbidity, mortality, and impaired quality of life. The current treatment for VAs is a catheter ablation procedure. This procedure is considered moderately successful at best and the success rate dramatically increases when the ablation is performed by experienced operators....

Published: 9/12/2025 | Inventor(s): Konstantinos Aronis, Ronald Berger, Natalia Trayanova, Shijie Zhou, Harikrishna Tandri

Keywords(s): Arrhythmias, Cardiovascular Diseases, Disease Indication, Image Display Software, Image Processing Software, Imaging and Sensing Systems, In Vivo Medical Imaging, Interventional and Surgical Systems, Surgical Navigation, Tracking Software

Category(s): Clinical and Disease Specializations > Cardiovascular > Arrhythmia, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Medical Devices > Surgical, Technology Classifications > Medical Devices > Cardiology

Developing the POTOMAC model: A Novel Prediction Model to Study the Impact of LymphOpenia kineTics on Survival Outcomes in Head and Neck Cancer via an Ensemble Tree-based MAChine Learning Approach

Survival Outcome Prediction Model for Lymphopenia in Head and Neck CancerJHU Ref #: [C17597]Unmet NeedLymphopenia, a disorder in which your blood doesn't have enough white blood cells, is a potential marker of survival outcomes for many solid tumors of the head and neck. Currently, researchers disagree on whether lymphopenia reflects the patient’s...

Published: 9/12/2025 | Inventor(s): Carmen Kut, Harry Quon

Keywords(s):

Category(s): Clinical and Disease Specializations > Oncology > Head & Neck Cancer, Technology Classifications > Computers, Electronics & Software > Precision Medicine Tools, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Computers, Electronics & Software > Algorithms, Clinical and Disease Specializations > Hematology

Personalized Care for Patients with Retinal Diseases

Unmet NeedAccording to the National Institute of Health, neovascular (wet) age-related macular degeneration (nAMD) is the most common cause of visual impairment among elderly patients in developed countries, and is predicted to increase globally from 196 million patients in 2020 to 288 million by 2040. Our current management of nAMD has two major limitations....

Published: 9/12/2025 | Inventor(s): Tin Yan Liu, Craig Jones

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Healthcare IT, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Computers, Electronics & Software > Machine Learning, Clinical and Disease Specializations > Ophthalmology > Age-Related Macular Degeneration

Augmented or Virtual Reality Based Evaluation of Visual Field

Sensitive visual field assessment using augmented realityJHU Ref #: C17601Unmet NeedWhile visual field measurement is key in diagnosing and monitoring eye and systemic diseases in patients (American Academy of Ophthalmology, 2022), current practices are either quick but imprecise (confrontation visual field tests that rely on the doctor’s hand gestures...

Published: 9/12/2025 | Inventor(s): Ali Saber Tehrani, Arash Saber Tehrani

Keywords(s):

Category(s): Clinical and Disease Specializations > Ophthalmology, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Machine Learning

OpenCRAVAT, An Open Source Collaborative Platform for the Annotation of Human Genetic Variation

Unmet NeedGene variants are complex to interpret, involving different published methods, databases, algorithms for ranking genes and different prediction tools. Decision support frameworks were created to integrate these various resources into one environment. However, current frameworks are limited by a closed proprietary architecture, limiting its...

Published: 9/12/2025 | Inventor(s): Rachel Karchin, Kymberleigh Pagel, Michael Ryan, Rick Kim, Kyle Moad

Keywords(s): Computer and Network Systems, Computer Software, Database Management Software

Category(s): Technology Classifications > Computers, Electronics & Software > Databases, Technology Classifications > Computers, Electronics & Software > Algorithms, Clinical and Disease Specializations > Genetic Diseases, Clinical and Disease Specializations > Oncology

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