Search Results - vesicle

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A versatile method to fabricate giant vesicles that can encapsulate a range of membrane-bound proteins, luminal proteins, and cell lysates under physiologically relevant conditions
Unmet NeedCreating artificial vesicular systems that can mimic natural cells continues to be a challenge in the fields of synthetic biology as well as gene and drug delivery. This class of artificial systems serve as a powerful platform for both studying biology in a minimal, controlled system and moreover can be used as biocompatible vehicles to deliver...
Published: 6/27/2024   |   Inventor(s): Shiva Razavi, Takanari Inoue, Tianzhi Luo, Douglas Robinson
Keywords(s): Drug Delivery Vehicle, Therapeutic Matter, Therapeutics, Vesicle
Category(s): Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms
Biomimetic Anisotropic Polymeric Particles with Naturally Derived Cell Membranes for Enhanced Drug Delivery
Unmet Need: Although biomimetic polymeric particles have been used for drug delivery, these particles have not been able to mimic the natural cell in terms of size, shape, mechanical properties, and surface features. This invention is a biomimetic particle platform that can be used to simulate natural cells found throughout the body.  Technology Overview:...
Published: 6/27/2024   |   Inventor(s): Jordan Green, Randall Meyer, Elana Ben-Akiva
Keywords(s): Drug Delivery Vehicle, Drug Delivery Vehicle Synthesis Method, Nanoparticles, Therapeutic Matter, Therapeutics, Vesicle
Category(s): Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Therapeutic Modalities
Engineered Anucleate Cellular and Extracellular Vesicles as a Novel Biologics Delivery Platform
UNMET NEED Biologic therapeutics, specifically antibodies, have demonstrated tremendous potential for treatment of a wide range of cancer types. Antibodies are designed to possess a strong affinity for a particular target, a very desirable characteristic for a drug. However, antibodies must be administered multiple times by injection, due to their...
Published: 6/27/2024   |   Inventor(s): Linzhao Cheng, Hao Bai, Vasiliki Machairaki
Keywords(s): Drug Delivery Vehicle, Therapeutic Matter, Therapeutics, Vesicle
Category(s): Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Therapeutic Modalities
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