Search Results - linzhao+cheng

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Human iPSC Lines Derived using Novel Plasmids

The Material consists of two induced pluripotent stem (iPS) cell lines derived from human bone marrow and cord blood.and plasmids used to create these virus-free and integration-free human iPS cell lines.

Published: 4/23/2026 | Inventor(s): Linzhao Cheng

Keywords(s): Basic Research Biomarker, Cell Model, Cloning Reagents, Discovery/Research Tools, In Vitro Research Tool, Plasmid, Research Reagent, Stem Cells

Category(s): Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Stem Cells, Technology Classifications > Research Tools > Vectors & Plasmids, Technology Classifications > Research Tools

Engineered Anucleate Cellular and Extracellular Vesicles as a Novel Biologics Delivery Platform

UNMET NEED Biologic therapeutics, specifically antibodies, have demonstrated tremendous potential for treatment of a wide range of cancer types. Antibodies are designed to possess a strong affinity for a particular target, a very desirable characteristic for a drug. However, antibodies must be administered multiple times by injection, due to their...

Published: 4/24/2026 | Inventor(s): Linzhao Cheng, Hao Bai, Vasiliki Machairaki

Keywords(s): Drug Delivery Vehicle, Therapeutic Matter, Therapeutics, Vesicle

Category(s): Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Technology Classifications > Therapeutic Modalities

Reprogramming Blood Cells from Healthy Donors and Patients to Pluripotent and Multipotent Stem Cells

C10865: Novel method to reprogram blood cells to pluripotent and multipotent stem cellsValue Proposition: JHU scientists have developed a method to reprogram human CB, adult bone marrow and peripheral blood cells from healthy donors without any pretreatment to pluripotent and multipotent stem cells. • This novel method uses easily accessible...

Published: 4/23/2026 | Inventor(s): Linzhao Cheng

Keywords(s): Cell Model, Discovery/Research Tools, Disease Indication, In Vitro Research Tool, Osteoporosis, Skeletal Disorders, Stem Cells, Translational Research Biomarker

Category(s): Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Stem Cells, Technology Classifications > Research Tools, Clinical and Disease Specializations > Endocrinology

Modulation of systemic Immune Responses by Transplantation of Hemotopoietic Stem Cells Transduced with Genes Encoding Antigens and Antigen Presenting Cell Regulatory Molecules

C03855: Modulation of Systemic Immune Responses by Transplantation of Hemotopoietic Stem Cells Transduced with Genes Encoding Antigens and Antigen Presenting Cell Regulatory Molecules Technical Details: The initiation of T cell-dependent immune responses depends on presentation of antigens by bone marrow-derived antigen-presenting cells such as...

Published: 4/23/2026 | Inventor(s): Yan Cui, Katherine Whartenby, Linzhao Cheng, Curt Civin, Drew Pardoll

Keywords(s): Biologics, Cancers, Cell Therapy/Gene Therapy, Cell Therapy/Immunotherapy, Combination, Disease Indication, Nucleic Acid, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type, Whole cell

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Cell Therapies, Technology Classifications > Therapeutic Modalities > Gene Therapies, Technology Classifications > Therapeutic Modalities > Immunotherapies, Technology Classifications > Therapeutic Modalities