Search Results - curt+civin

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Human Stem Cells and Monoclonal Antibodies (MY-10)

Human Stem Cells and Monoclonal Antibodies (MY-10) Case Number C02182 ABSTRACT Monoclonal antibodies that recognize a stage-specific antigen on immature human marrow cells. These antibodies are useful in methods of isolating cell suspensions from human blood and marrow that can be employed in bone marrow transplantation. Cell suspensions containing...

Published: 3/13/2025 | Inventor(s): Curt Civin

Keywords(s): Antibodies, Biologics, Bone Marrow, Bone Marrow Transplant, Cell Therapy, Disease Indication, Single, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type, Transplants

Category(s): Clinical and Disease Specializations, Technology Classifications > Therapeutic Modalities > Antibodies, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Cell Therapies, Technology Classifications > Therapeutic Modalities, Clinical and Disease Specializations > Transplantation, Clinical and Disease Specializations > Transplantation > Bone Marrow Transplant

Hybridoma (MY-31)

TITLE Hybridoma (MY-31) CASE NUMBER C09194 DESCRIPTION CD56, clone MY31, is derived by immunizing (C57BL/6 x BALB/c) F1 mice with the KG1a cell line and fusing the immune splenocytes with the SP2/0 myeloma cell line. CD56 recognizes an antigen present on natural killer (NK) lymphocytes. PUBLICATION Lanier, L.L., Le, A.M., Civin, C.I., Loken,...

Published: 3/13/2025 | Inventor(s): Curt Civin

Keywords(s): Basic Research Biomarker, Cell Model, Discovery/Research Tools, Hybridomas, In Vitro Research Tool

Category(s): Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools

Transcriptome of Human Hematopoietic Stem Cells

C04191: Therapeutic and Diagnostic Applications of Genes Differentially Expressed in Lympho-hematopoietic Stem Cells Technical Details: The human CD34+/CD38-/Lin- cell subset comprises ~1-10% of the CD34+ cell population and includes few of the less primitive hematopoietic (lineage-committed) progenitor cells (HPCs), yet contains most of the primitive...

Published: 3/13/2025 | Inventor(s): Robert Georgantas, Curt Civin

Keywords(s): Basic Research Biomarker, Cell Model, Discovery/Research Tools, In Vitro Research Tool, Stem Cells

Category(s): Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Research Tools > Stem Cells, Technology Classifications > Diagnostics, Technology Classifications > Research Tools

Modulation of systemic Immune Responses by Transplantation of Hemotopoietic Stem Cells Transduced with Genes Encoding Antigens and Antigen Presenting Cell Regulatory Molecules

C03855: Modulation of Systemic Immune Responses by Transplantation of Hemotopoietic Stem Cells Transduced with Genes Encoding Antigens and Antigen Presenting Cell Regulatory Molecules Technical Details: The initiation of T cell-dependent immune responses depends on presentation of antigens by bone marrow-derived antigen-presenting cells such as...

Published: 3/13/2025 | Inventor(s): Yan Cui, Katherine Whartenby, Linzhao Cheng, Curt Civin, Drew Pardoll

Keywords(s): Biologics, Cancers, Cell Therapy/Gene Therapy, Cell Therapy/Immunotherapy, Combination, Disease Indication, Nucleic Acid, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type, Whole cell

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Cell Therapies, Technology Classifications > Therapeutic Modalities > Gene Therapies, Technology Classifications > Therapeutic Modalities > Immunotherapies, Technology Classifications > Therapeutic Modalities