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Search Results - hybridomas
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Hybridoma expressing anti-RG-1 mAb for the study of human papillomavirus L2
Technology DescriptionJHU scientists generated a hybridoma expressing a monoclonal antibody, RG-1, that binds to highly conserved L2 residues and neutralizes human papillomavirus 16 (HPV16) and HPV18. Passive immunotherapy with RG-1 was protective in mice. Antiserum to the HPV16 L2 peptide comprising conserved residues neutralized pseudoviruses HPV5,...
Published: 3/13/2025
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Inventor(s):
Ratish Gambhira
,
Richard Roden
Keywords(s):
Antibodies
,
Basic Research Biomarker
,
Cell Model
,
Discovery/Research Tools
,
Hybridomas
,
In Vitro Research Tool
,
Monoclonal Antibodies
,
Research Reagent
Category(s):
Technology Classifications > Research Tools > Antibodies
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Technology Classifications > Research Tools > Cell Lines
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Technology Classifications > Research Tools
Hybridoma (MY-31)
TITLE Hybridoma (MY-31) CASE NUMBER C09194 DESCRIPTION CD56, clone MY31, is derived by immunizing (C57BL/6 x BALB/c) F1 mice with the KG1a cell line and fusing the immune splenocytes with the SP2/0 myeloma cell line. CD56 recognizes an antigen present on natural killer (NK) lymphocytes. PUBLICATION Lanier, L.L., Le, A.M., Civin, C.I., Loken,...
Published: 3/13/2025
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Inventor(s):
Curt Civin
Keywords(s):
Basic Research Biomarker
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Cell Model
,
Discovery/Research Tools
,
Hybridomas
,
In Vitro Research Tool
Category(s):
Technology Classifications > Research Tools > Antibodies
,
Technology Classifications > Research Tools > Cell Lines
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Technology Classifications > Research Tools
Hybridoma Clone PVALD 434-3 4A4.2E12 or PVALD 434-3 4A4.6B10 Producing Monoclonal Antibody to Pfalciparum Aldolase or Monoclonal Antibody Purified from same Hybridoma
C10647: Monoclonal Antibody to Pfalciparum Aldolase (Hybridoma Clone PVALD 434-3 4A4.2E12 or PVALD 434-3 4A4.6B10) Value Proposition: • This technology has an application to address a major patient need. • The ability to reliably diagnose malaria infections. • The monoclonal antibodies specific to aldolase. Technical Details: Malaria is...
Published: 3/13/2025
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Inventor(s):
David Sullivan
Keywords(s):
Antibodies
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Basic Research Biomarker
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Biomarker
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Cell Model
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Clinical Diagnostics
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Diagnostic Biomarker
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Discovery/Research Tools
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Disease Indication
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Hybridomas
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In Vitro Diagnostics
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In Vitro Research Tool
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Infectious Diseases
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Malaria
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Monoclonal Antibodies
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Parasitic Infections
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Research Reagent
Category(s):
Clinical and Disease Specializations
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Clinical and Disease Specializations > Infectious Diseases > Malaria
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Clinical and Disease Specializations > Infectious Diseases > Parasitic Infections
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Technology Classifications > Diagnostics > Biomarkers
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Technology Classifications > Diagnostics > Diagnostic Biomarkers
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Technology Classifications > Diagnostics > In Vitro Diagnostics
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Technology Classifications > Research Tools > Antibodies
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Technology Classifications > Research Tools > Cell Lines
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Technology Classifications > Diagnostics
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Clinical and Disease Specializations > Infectious Diseases
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Technology Classifications > Research Tools
Hybridoma Clone G6
C10552: Hybridoma Secreting Anti-Excitatory Amino Acid Transporter 2 (EAAT2) AntibodyNovelty: Hybridoma cell line that secretes monoclonal antibody to GLT1/EAAT2 protein.Value Proposition: Mutations or decreased expression of the GLT1/EAAT2 protein are associated with amyotrophic lateral sclerosis and thus the detection of protein can be used as an...
Published: 3/13/2025
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Inventor(s):
Jeffrey Rothstein
Keywords(s):
Amyotrophic Lateral Sclerosis
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Basic Research Biomarker
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Cell Lines
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Cell Model
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CNS and Neurological Disorders
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Discovery/Research Tools
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Disease Indication
,
Human Cell Lines
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Hybridomas
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In Vitro Research Tool
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Translational Research Biomarker
Category(s):
Technology Classifications > Research Tools > Antibodies
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Technology Classifications > Research Tools > Cell Lines
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Technology Classifications > Research Tools
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Clinical and Disease Specializations > Rare Diseases
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Clinical and Disease Specializations > Neurology > Amyotrophic Lateral Sclerosis
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Technology Classifications > Research Tools > Human Cell Lines
CD19 Hybridoma
C09951: Hybridoma Cell Line Secreting Mouse CD19 AntibodyNovelty: Hybridoma cell line (1D3) secreting the monoclonal antibody against the murine homologue of B-cell CD19 protein.Value Proposition: CD19 is a B lymphocyte-lineage antigen and has been associated with cancer progression, notably B-cell lymphomas. Therefore, extensive animal model study...
Published: 3/13/2025
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Inventor(s):
Ian Krop
,
Douglas Fearon
Keywords(s):
Basic Research Biomarker
,
Cell Model
,
Discovery/Research Tools
,
Hybridomas
,
In Vitro Research Tool
Category(s):
Technology Classifications > Research Tools > Antibodies
,
Technology Classifications > Research Tools > Cell Lines
,
Technology Classifications > Research Tools
R-3327-AT6.1
C03847: R-3327-AT6.1 Technical Details: Somatic cell hybrids created from highly metastatic rat prostatic cancer cells and human chromosome 11 were created using micro cell-mediated chromosome transfer. The introduction of human chromosome 11 into the highly metastatic rat prostate cancer cells suppressed the metastatic ability of the cells without...
Published: 3/13/2025
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Inventor(s):
John Isaacs
Keywords(s):
Basic Research Biomarker
,
Cell Model
,
Discovery/Research Tools
,
Hybridomas
,
In Vitro Research Tool
Category(s):
Technology Classifications > Research Tools > Cell Lines
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Technology Classifications > Therapeutic Modalities > Targets
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Technology Classifications > Research Tools
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Technology Classifications > Therapeutic Modalities
Hybridoma H5C6
C03188: Hybridoma H5C6 Technical Details: A murine hybridoma cell line that secretes a monoclonal antibody (IgG1, k) against hum CD63.Looking for Partners: Useful tool for immunophenotyping, immunohistochemistry, immunoprecipitation, Western blot analysis, and immunocapture assays.Publications:Blood 1991 77:121-132
Published: 3/13/2025
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Inventor(s):
James Hildreth
Keywords(s):
Antibodies
,
Basic Research Biomarker
,
Cell Model
,
Discovery/Research Tools
,
Hybridomas
,
In Vitro Research Tool
,
Monoclonal Antibodies
,
Research Reagent
Category(s):
Technology Classifications > Research Tools > Antibodies
,
Technology Classifications > Research Tools > Cell Lines
,
Technology Classifications > Research Tools
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