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Novel Fluoride Prenatal Dietary Supplement

INVENTION NOVELTYJHU researchers have developed a novel prenatal dietary supplement containing 3 mg of fluoride and a unique composition of a prenatal vitamin. VALUE PROPOSITIONAlthough the Institute of Medicine has indicated 3mg of fluoride as adequate intake for pregnant women since 1997, there is no existing prenatal vitamin on the market with this...

Published: 7/4/2024 | Inventor(s): Irina Burd, Flavia Brancusi, Darby Glenn

Keywords(s): Disease Indication, Drug Delivery Vehicle, Non-novel, Predicted Novelty, Pregnancy, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics, Womens Health, Women's Health

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Reproductive Health > Pregnancy, Clinical and Disease Specializations > Women's Health, Technology Classifications > Therapeutic Modalities > Small Molecules, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms, Clinical and Disease Specializations > Reproductive Health, Technology Classifications > Therapeutic Modalities

SR-BI as a Predictor of Human Female Infertility and Responsiveness to Treatment

Unmet Need:Approximately 48.5 million couples are infertile worldwide. Approximately 15% of couples in the United States are involuntarily infertile. Professional intervention can help about 40% of these couples achieve a pregnant state. A causative factor for the infertility relating to the woman is found in no more than one-half of couples that are...

Published: 7/4/2024 | Inventor(s): Annabelle Rodriguez

Keywords(s): Biomarker, Clinical Diagnostics, Diagnostic Biomarker, Disease Indication, Fertility, In Vitro Diagnostics, Womens Health, Women's Health

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Reproductive Health > Fertility, Clinical and Disease Specializations > Women's Health, Technology Classifications > Diagnostics > Biomarkers, Technology Classifications > Diagnostics > Diagnostic Biomarkers, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Diagnostics, Clinical and Disease Specializations > Reproductive Health

C12023: Autologous Adult Stem Cell Therapy for Prevention of Pre-Term Birth

Unmet NeedPreterm birth is among the top causes of death in infants worldwide. Preterm birth affects 12% of obstetrical outcomes and is associated with significant short term and long term public health ramifications for the children born in that setting. Currently, there are no effective therapies that significantly reduce uterine contractions to...

Published: 7/4/2024 | Inventor(s): Seyed Fatemi, Michael Johnston, Karin Blakemore, Irina Burd

Keywords(s): Biologics, Cell Therapy, Disease Indication, Inflammatory Disorders, Pregnancy, Preterm, Single, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type, Whole cell, Womens Health, Women's Health

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Inflammation, Clinical and Disease Specializations > Reproductive Health > Pregnancy, Clinical and Disease Specializations > Reproductive Health > Preterm, Clinical and Disease Specializations > Women's Health, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Cell Therapies, Clinical and Disease Specializations > Reproductive Health, Technology Classifications > Therapeutic Modalities

Probe for measuring Bioimpedance of the Human Uterine Cervix

C04241: Probe for measuring Bioimpedance of the Human Uterine Cervix Technical Details: There are various clinical conditions, both normal and abnormal, where significant remodeling of the proteins in the human uterine cervix occurs. For example, with increased secretion of decorin in late pregnancy and labor, collagen (the main component of the...

Published: 7/4/2024 | Inventor(s): Ashkon Shaahinfar, Kenny Hwee Seong Ching, Somponnat Sampattavanich, Yen Shi Hoe, Melanie Ruffner, Elbert Shangnung Hu, Edith Diament Allen

Keywords(s): Cancers, Cervical Cancer, Disease Indication, Electrical Impedance Probe, Imaging and Sensing Systems, Imaging Probe/Transducer, In Vivo Medical Imaging, Interventional and Surgical Systems, Probes, Surgical Instruments, Womens Health, Women's Health

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Women's Health, Technology Classifications > Computers, Electronics & Software > Sensors, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Medical Devices, Clinical and Disease Specializations > Oncology > Cervical Cancer

Enhancement of DNA Vaccine Potency by Linking Marek's Disease Virus Type 1 VP22 to an Antigen

C03895: Enhancement of DNA Vaccine Potency by Linking Marek's Disease Virus Type 1 VP22 to an Antigen Technical Details: We have previously employed an spreading strategy using herpes simplex virus type 1 (HSV-1) VP22 protein to enhance DNA vaccine potency because DNA vaccines lack the intrinsic ability to amplify in cells. Recently, studies have demonstrated...

Published: 7/4/2024 | Inventor(s): Chien-Fu Hung, T.c. Wu

Keywords(s): Biologics, Cancers, Cervical Cancer, Disease Indication, Immunotherapy, Nucleic Acid, Single, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type, Vaccine, Womens Health, Women's Health

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology > Cervical Cancer, Clinical and Disease Specializations > Women's Health, Technology Classifications > Therapeutic Modalities, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Immunotherapies, Technology Classifications > Therapeutic Modalities > Vaccines, Clinical and Disease Specializations > Oncology

Superior Molecular Vaccine Linking the Translocation Domain of a Bacterial Toxin to an Antigen

UNMET NEED: Enhancement of antigen presentation through the MCH class I pathway to CD8+ T cells has been a primary focus of cancer immunotherapy. DNA vaccines have emerged as attractive approaches to generate CD8+ T cell responses in vaccinated humans. Yet, lack of potency and immunogenicity has limited their clinical utility to date. Disclosed herein...

Published: 7/4/2024 | Inventor(s): Chien-Fu Hung, T.c. Wu

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology > Cervical Cancer, Clinical and Disease Specializations > Women's Health, Technology Classifications > Therapeutic Modalities, Technology Classifications > Therapeutic Modalities > Biologics, Technology Classifications > Therapeutic Modalities > Gene Therapies, Technology Classifications > Therapeutic Modalities > Immunotherapies, Technology Classifications > Therapeutic Modalities > Vaccines, Clinical and Disease Specializations > Oncology