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shRNA knockdown vectors to inhibit expression of specific nuclear Lamin proteins and variants

Invention novelty:JHU researchers have designed and tested several several shRNA knockdown vectors that can inhibit specific isotypes of lamin proteins as well as variants that cause disease.Value Proposition:Many disease arise form aberration in proteins of the nuclear lamina. The researchers have designed and are testing several shRNA knockdown vectors...

Published: 3/13/2025 | Inventor(s): Xianrong Wong, Karen Reddy

Keywords(s): Basic Research Biomarker, Cloning Reagents, Discovery/Research Tools, Plasmid, Research Reagent

Category(s): Technology Classifications > Research Tools > Vectors & Plasmids, Technology Classifications > Research Tools