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Spectral DSA

Unmet NeedCT angiography with digital subtraction (DSA) is the standard diagnostic imaging method for cardiovascular abnormalities (1). This technique captures images both before and after injection of radiopaque contrast; images are then subtracted from one another, leaving only contrast enhanced vasculature in the final image. While DSA is the gold...

Published: 3/14/2025 | Inventor(s): Joseph Stayman, Jianan Gang

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Diagnostics > Diagnostic Imaging, Technology Classifications > Medical Devices > Imaging, Technology Classifications > Research Tools > Imaging, Clinical and Disease Specializations > Cardiovascular > Aneurysm, Clinical and Disease Specializations > Cardiovascular > Vascular Diseases, Clinical and Disease Specializations > Neurology > Cerebral Aneurysm, Clinical and Disease Specializations > Neurology > Cerebral Ischemia, Clinical and Disease Specializations > Neurology > Hemorrhage

An Oscillatory Atherectomy Device Incorporating a Novel Burr Design and Torque Limiting System for the Safer Treatment of Advanced Coronary Artery Disease

Unmet NeedCardiovascular disease is the leadind cause of death globally and the most significant cost contributor to the health care system. When coronary plaques become heavily calcified - which is typical in older patients with long-standing coronary disease and those with co-morbidities such as chronic kidney disease - the compliance of the vessel...

Published: 3/13/2025 | Inventor(s): Caitlin Romanczyk, Peter Johnston, Chao-Wei Hwang, George Coles, Clayton Andrews, Joshua Punnoose, Quinn Salditch, Scott Sterrett, Zachary Buono, Paige Frank, Ananya Gupta

Keywords(s): Atherosclerosis, Cardiovascular Diseases, Disease Indication, Interventional and Surgical Systems, Irrigation/Drainage Tools, Mechanical Cutters/Incision Tools, Surgical Instruments, Vascular Diseases

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular > Atherosclerosis, Clinical and Disease Specializations > Cardiovascular > Vascular Diseases, Technology Classifications > Medical Devices > Surgical, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Medical Devices

Method to Measure Wall Motion and Wall Thickness Using Contrast Enhanced Fluoroscopy

C11284 Method to Measure Wall Motion and Wall Thickness Using Contrast Enhanced Fluoroscopy BackgroundMost invasive angiograms end in the measurement of heart function by performing a ventriculogram. Performance of left ventriculography (LVG) requires additional contrast agent (about 30 – 40ml), catheter and time. Scientists at Johns Hopkins...

Published: 3/13/2025 | Inventor(s): Joao A. C. Lima, Hisato Takemoto, Takuya Sakaguchi, Jeff Trost, Richard George

Keywords(s): Atherosclerosis, Cardiovascular Diseases, Disease Indication, Fluoroscopy, Image Display Hardware, Image Display Software, Image Processing Software, Imaging and Sensing Systems, Imaging Modality, In Vivo Medical Imaging, Vascular Diseases

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular > Atherosclerosis, Clinical and Disease Specializations > Cardiovascular > Vascular Diseases, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Computers, Electronics & Software > Image Processing & Analysis, Technology Classifications > Medical Devices > Imaging, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Medical Devices

Novel Class and Clinical Application of Antithrombotic Agents that Specifically Inhibit Inflammation-related Vascular Occlusion

C05005: Novel Class and Clinical Application of Antithrombotic Agents that Specifically Inhibit Inflammation-related Vascular Occlusion Technical Details: Inflammation is known to be an integral part of the vascular occlusive events that occur during heart attack and stroke, although the specific pathway that links inflammation to clot formation...

Published: 3/13/2025 | Inventor(s): Nauder Faraday

Keywords(s): Biologics, Biomarker, Cardiovascular Diseases, Disease Indication, Mechanism-of-action Biomarker, Peptide, Single, Targeted Therapy, Therapeutic Matter, Therapeutic Substance, Therapeutics, Therapy Type, Vascular Diseases, Vascular Occlusion

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular > Vascular Diseases, Technology Classifications > Therapeutic Modalities > Peptides, Technology Classifications > Therapeutic Modalities > Targets, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Therapeutic Modalities

Ambulatory Raynaud's Monitor

C03944: Ambulatory Raynaud's Monitor Technical Details: Monitoring a person?s response to cold by recording their skin temperature is a key physiological response parameter for identifying Raynaud?s. This device would provide the means for physicians to definitively diagnose the disease without having to rely solely on a patient?s subjective feedback....

Published: 3/13/2025 | Inventor(s): Binh Le, David Stott, Ark Lew, Robert Wise, Paul Schwartz, Fredrick Wigley

Keywords(s): Cardiovascular Diseases, Clinical Diagnostics, Diagnostic Tool, Disease Indication, Measurement Tool, Raynaud's, Vascular Diseases

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Cardiovascular > Raynaud's, Clinical and Disease Specializations > Cardiovascular > Vascular Diseases, Technology Classifications > Diagnostics > In Vivo Diagnostics, Clinical and Disease Specializations > Cardiovascular, Technology Classifications > Diagnostics