Search Results - clinical+and+disease+specializations+%3e+infectious+diseases+%3e+covid-19

11 Results

Sort By:

Compositions and Methods for Treating Diseases and Conditions Associated with Activation of the NLRP3 Inflammasome

Unmet NeedAutoinflammatory responses, your body’s innate defense mechanism against infections and stressors, can become overactive and cause chronic inflammation in various tissues and organs. Inflammatory diseases affect more than 200 million people worldwide and include pulmonary hypertension, scleroderma, rheumatoid arthritis, pulmonary fibrosis,...

Published: 3/14/2025 | Inventor(s): Roger Johns

Keywords(s):

A DNA Vaccine for Eliciting T Cell Immunity in the Lung

Unmet NeedRespiratory pathogens are a major contributor to global economic and public health crises. In the wake of the COVID-19 pandemic, new vaccine technologies have been developed to improve the response to emerging pathogens. However, questions remain regarding how to deal with pathogens that have the potential to cause future pandemics. New vaccination...

Published: 3/14/2025 | Inventor(s): Richard Markham, James Gordy, Petros Karakousis

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases > Covid-19, Clinical and Disease Specializations > Infectious Diseases > Tuberculosis (TB), Technology Classifications > Therapeutic Modalities > Vaccines

Aerosol Biosensor for Preclinical Detection of Coronavirus

Unmet NeedCurrent testing methods for COVID-19 can provide results in as little as 24 hours and as long as 10 days, depending on the testing method and the location. Self-quarantining of infected individuals is vital when they are spreading the virus, and these tests are necessary to monitor the spread of the disease, in order to emphasize community...

Published: 3/14/2025 | Inventor(s): Chao Wang, Hongpeng Jia, Mukund Madhav Goyal

Keywords(s):

Category(s): Clinical and Disease Specializations > Respiratory Diseases, Clinical and Disease Specializations > Infectious Diseases > Covid-19, Technology Classifications > Diagnostics

P-selectin inhibitor, compositions thereof and methods of use thereof

Unmet NeedCOVID-19 is characterized by vascular inflammation and thrombosis, including elevations in P-selectin, a mediator of inflammation released by endothelial cells. Patients with serious infection are more likely to have COVID-19 associated coagulopathy than patients with mild infection, and those who die from COVID-19 are more likely to have...

Published: 3/14/2025 | Inventor(s): Charles Lowenstein

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases > Covid-19, Technology Classifications > Therapeutic Modalities, Clinical and Disease Specializations > Inflammation

Repeatable Autonomous Robotic Ultrasound Scanning System

Unmet Need:Ultrasound imaging is often performed at the lungs as a point of care test for various scenarios, such as analyzing traumatic injury, diagnosing lung pathologies, and monitoring disease progression, or as a guidance technique for certain interventions. Such imaging requires a highly skilled operator in order to generate precise and accurate...

Published: 3/14/2025 | Inventor(s): Axel Krieger, Thorsten Fleiter, Lidia Al-Zogbi

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Robotics, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Algorithms, Clinical and Disease Specializations > Traumatic Injury, Clinical and Disease Specializations > Infectious Diseases > Covid-19

Hemagglutination-based Assay for Coronavirus Antibody Detection and Titering

Unmet NeedThe SARS-CoV-2 virus causing COVID-19 disease represents a globally growing pandemic infection. The virus has infected 20.6 million individuals and results in 746,000 deaths as of August 2020. In order to keep the infection at bay and to keep others safe, it is important to test and detect SARS-CoV-2 as soon as possible. PCR is the gold standard...

Published: 3/14/2025 | Inventor(s): Robert Kruse, Zack Wang, Yuting Huang

Keywords(s):

Category(s): Technology Classifications > Diagnostics, Clinical and Disease Specializations > Infectious Diseases > Covid-19

Aptamer-based Electrochemical Virus Sensor

#C16928: Aptamer-based Electrochemical Virus SensorInventor(s): Yuxuan Wang, Chao Wang, Hongpen Jia, Mukund Madhav GoyalUnmet NeedTests for viral infections have made a statement return to the forefront of medical technology research in the wake of the COVID-19 pandemic, which has claimed the lives of 4,361,996 individuals globally. The global market...

Published: 3/14/2025 | Inventor(s): Chao Wang, Yuxuan Wang, Hongpeng Jia, Mukund Madhav Goyal

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases > Covid-19, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Diagnostics

HIV-1 Latency Cell Line Construction

Unmet NeedApproximately 38 million people are currently living with human immunodeficiency virus (HIV) globally. HIV is a serious health issue, and around 1 million people die from HIV/AIDS related illnesses each year. Currently, there is no cure for HIV, only prevention and treatment techniques exist. Current methods of treatment use antiretroviral...

Published: 3/14/2025 | Inventor(s): Robert Siliciano, Weiwei Dai

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases > Covid-19, Technology Classifications > Research Tools > Cell Lines

Utility of N501Y + 19del + D614G Variant SARS-CoV-2 Pseudoviruses for COVID-19 Mouse Modeling

Unmet Need: Globally, there are more than 213,000,000 confirmed cases of COVID-19, including more than 4,448,000 deaths reported to the World Health Organization (WHO) (WHO, 2021) by August 25th, 2021. The number of cases and deaths increase each day. Various animal models have been used to study COVID-19 with varying susceptibility due to species-specific...

Published: 3/14/2025 | Inventor(s): Chien-Fu Hung, Brandon Lam, Ya Chea Tsai, T.c. Wu

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases > Covid-19, Technology Classifications > Research Tools > Viruses

COVID-19 Baseline Prediction Model

Unmet NeedThe first case of coronavirus disease 2019 (COVID- 19) in the United States was identified on 20 January 2020 in a returned traveler from Wuhan, China. By early August 2020, about one quarter of the world's cases and deaths were in the United States. Outcomes range from asymptomatic infection to death. Age; sex; smoking; race; body mass...

Published: 3/14/2025 | Inventor(s): Brian Garibaldi, Scott Zeger, Amita Gupta, Mei-Cheng Wang, Karen Bandeen-Roche, John Muschelli, Joshua Betz, Jamie Perin, Grant Schumock, Jacob Fiksel, Martina Fu

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases > Covid-19, Technology Classifications > Computers, Electronics & Software > Algorithms

1 2