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Real-Time Prediction of Cardiovascular Complications of COVID-19 Using Machine Learning and High-Dimensional Clinical Data

Value Proposition:· High accuracy in predicting both all-cause mortality/cardiac arrest and thromboembolic events in hospitalized COVID-19 patients, with clinically meaningful early warning times. · Real-time patient risk assessment based on clinical data, via a continuously updating risk score for an outcome within a specific timeframe....

Published: 9/12/2025 | Inventor(s): Natalia Trayanova, Ashish Doshi, Eric Sung, Allison Hays, Julie Shade

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases > Covid-19, Technology Classifications > Computers, Electronics & Software > Machine Learning

Predictive Algorithms for MISKD Clinical Decision Support System

Unmet NeedChildren hospitalized with SARS-Cov-2 infection are at risk for two similar inflammatory syndromes: Kawasaki disease (KD), and multi-system inflammatory syndrome in children (MIS-C). However, current clinical diagnostic standards for these two conditions have considerable overlap, which can lead to misdiagnosis and suboptimal treatment and...

Published: 9/12/2025 | Inventor(s): Cedric Manlhiot, Bhargava Kumar Chinni, Shelby Kutty

Keywords(s):

Category(s): Clinical and Disease Specializations, Technology Classifications > Diagnostics > In Vitro Diagnostics, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Clinical and Disease Specializations > Infectious Diseases > Covid-19, Clinical and Disease Specializations > Inflammation

Short Viral RNAs (svRNAs) with Theragnostic Potential in Infection with SARS-CoV-2 and Related Viruses

Value PropositionNovel Biomarkers for Diagnosis & PrognosisInsights into viral immune evasion mechanism Identify key host pathways targeted by svRNAs Novel Therapeutic TargetsIdentified pathways enable the development of immune-modulating therapies. Unmet NeedStudies have show than SARS-CoV-2 employs various mechanisms to evade the host’s innate...

Published: 9/12/2025 | Inventor(s): Kenneth Witwer, Tom Driedonks, Andrey Turchinovich

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases > Covid-19, Technology Classifications > Therapeutic Modalities, Technology Classifications > Research Tools > Nucleic Acids, Clinical and Disease Specializations > Infectious Diseases

COVID.AI: Intelligent COVID Radiological Assessment and Diagnostic System and Methods :IC-RADS

Inventor(s): Vishwa Sanjay Parekh, Michael A. Jacobs Unmet Need:The COVID-19 pandemic, caused by SARS-CoV-2, has resulted in more than 365,000 deaths in the United States and over 1.9 million deaths worldwide. Diagnosis of COVID-19 has been largely limited to molecular and serologic tests, which are not indicative of the severity nor the progression...

Published: 9/12/2025 | Inventor(s): Michael Jacobs, Vishwa Parekh

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases > Covid-19, Technology Classifications > Computers, Electronics & Software > Machine Learning, Technology Classifications > Diagnostics

Compositions and Methods for Treating Diseases and Conditions Associated with Activation of the NLRP3 Inflammasome

Unmet NeedAutoinflammatory responses, your body’s innate defense mechanism against infections and stressors, can become overactive and cause chronic inflammation in various tissues and organs. Inflammatory diseases affect more than 200 million people worldwide and include pulmonary hypertension, scleroderma, rheumatoid arthritis, pulmonary fibrosis,...

Published: 9/12/2025 | Inventor(s): Roger Johns

Keywords(s):

A DNA Vaccine for Eliciting T Cell Immunity in the Lung

Unmet NeedRespiratory pathogens are a major contributor to global economic and public health crises. In the wake of the COVID-19 pandemic, new vaccine technologies have been developed to improve the response to emerging pathogens. However, questions remain regarding how to deal with pathogens that have the potential to cause future pandemics. New vaccination...

Published: 9/12/2025 | Inventor(s): Richard Markham, James Gordy, Petros Karakousis

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases > Covid-19, Clinical and Disease Specializations > Infectious Diseases > Tuberculosis (TB), Technology Classifications > Therapeutic Modalities > Vaccines

Aerosol Biosensor for Preclinical Detection of Coronavirus

Unmet NeedCurrent testing methods for COVID-19 can provide results in as little as 24 hours and as long as 10 days, depending on the testing method and the location. Self-quarantining of infected individuals is vital when they are spreading the virus, and these tests are necessary to monitor the spread of the disease, in order to emphasize community...

Published: 9/12/2025 | Inventor(s): Chao Wang, Hongpeng Jia, Mukund Madhav Goyal

Keywords(s):

Category(s): Clinical and Disease Specializations > Respiratory Diseases, Clinical and Disease Specializations > Infectious Diseases > Covid-19, Technology Classifications > Diagnostics

Repeatable Autonomous Robotic Ultrasound Scanning System

Unmet Need:Ultrasound imaging is often performed at the lungs as a point of care test for various scenarios, such as analyzing traumatic injury, diagnosing lung pathologies, and monitoring disease progression, or as a guidance technique for certain interventions. Such imaging requires a highly skilled operator in order to generate precise and accurate...

Published: 9/12/2025 | Inventor(s): Axel Krieger, Thorsten Fleiter, Lidia Al-Zogbi

Keywords(s):

Category(s): Technology Classifications > Computers, Electronics & Software > Robotics, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Computers, Electronics & Software > Algorithms, Clinical and Disease Specializations > Traumatic Injury, Clinical and Disease Specializations > Infectious Diseases > Covid-19

Hemagglutination-based Assay for Coronavirus Antibody Detection and Titering

Unmet NeedThe SARS-CoV-2 virus causing COVID-19 disease represents a globally growing pandemic infection. The virus has infected 20.6 million individuals and results in 746,000 deaths as of August 2020. In order to keep the infection at bay and to keep others safe, it is important to test and detect SARS-CoV-2 as soon as possible. PCR is the gold standard...

Published: 9/12/2025 | Inventor(s): Robert Kruse, Zack Wang, Yuting Huang

Keywords(s):

Category(s): Technology Classifications > Diagnostics, Clinical and Disease Specializations > Infectious Diseases > Covid-19

Aptamer-based Electrochemical Virus Sensor

#C16928: Aptamer-based Electrochemical Virus SensorInventor(s): Yuxuan Wang, Chao Wang, Hongpen Jia, Mukund Madhav GoyalUnmet NeedTests for viral infections have made a statement return to the forefront of medical technology research in the wake of the COVID-19 pandemic, which has claimed the lives of 4,361,996 individuals globally. The global market...

Published: 9/12/2025 | Inventor(s): Chao Wang, Yuxuan Wang, Hongpeng Jia, Mukund Madhav Goyal

Keywords(s):

Category(s): Clinical and Disease Specializations > Infectious Diseases > Covid-19, Clinical and Disease Specializations > Infectious Diseases, Technology Classifications > Computers, Electronics & Software > Algorithms, Technology Classifications > Computers, Electronics & Software > Artificial Intelligence, Technology Classifications > Diagnostics

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