Search Results - clinical+and+disease+specializations+%3e+ophthalmology+%3e+glaucoma

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Method to Measure Mechanical Strain in the Optic Nerve Head of Glaucoma Patients

Value Proposition: Non-invasive measurement of glaucoma progression and response to medicationApplicable for use on existing optical coherence tomography (OCT) imaging dataQuantifiable and dynamic biomarker of intraocular pressure-related changes to the eyePatient-specific approach to assess glaucoma risk and progressionTechnology Description: Researchers...

Published: 6/28/2024 | Inventor(s): Thao Nguyen, Harry Quigley, Cameron Czerpak, Vanessa Hannay, Dan Midgett

Keywords(s):

Category(s): Clinical and Disease Specializations > Ophthalmology, Clinical and Disease Specializations > Ophthalmology > Glaucoma, Technology Classifications > Diagnostics, Technology Classifications > Diagnostics > In Vivo Diagnostics

LACRIMAL CANALICULAR DELIVERY SYSTEM AND METHODS OF USE

Unmet NeedThere has been a growing development of novel drug delivery implants and tear drainage occlusion devices designed for delivery in the canalicular space. These implants are delivered through the punctal os, or the entrance to the lacrimal canicular space. These current strategies require the end user to manually insert the introducer at the...

Published: 6/27/2024 | Inventor(s): Bradley Barnett, Albert Jun

Keywords(s): Disease Indication, Drug Delivery Device, Dry Eye Syndrome, Eye Disorders, Glaucoma, Implanted Device, Implants, Therapeutic Devices, Therapeutics

Category(s): Clinical and Disease Specializations > Ophthalmology > Glaucoma, Clinical and Disease Specializations > Ophthalmology > Dry Eye Syndrome, Technology Classifications > Therapeutic Modalities > Therapeutic Delivery Platforms

Partially degradable glaucoma stent for controlled intraocular pressure reduction

UNMET NEED There are a number of parameters that affect the electrospinning process including polymer, solvent, polymer: solvent ratio, flow rate, voltage, distance to collector, collector type and speed, and needle size.5 Typical electrospinning setups allow for the manufacture of aligned or random fiber mats composed of nano- or micro-fibers. These...

Published: 6/27/2024 | Inventor(s): Kunal Parikh, Ian Pitha, Justin Hanes

Keywords(s): Disease Indication, Eye Disorders, Glaucoma, Implanted Device, Implants, Stent, Therapeutic Devices, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Ophthalmology > Glaucoma, Technology Classifications > Medical Devices > Therapeutic Devices, Technology Classifications > Medical Devices, Clinical and Disease Specializations > Ophthalmology

Novel Inhibitors of Protein Kinase Signaling that are Neuroprotective and have Potential Applicability for the Treatment of Glaucoma, Optic Nerve Disease, and other Forms of Neurodegeneration

Glaucoma is a major cause of visual loss and blindness in elderly Americans and throughout the world. One approach to treatment of glaucoma, and other optic nerve diseases as well as other neurodegenerations, is to develop “neuroprotective” agents that promote the survival of neurons. We have synthesized and tested a number of novel compounds, based...

Published: 6/27/2024 | Inventor(s): Tomas Vojkovsky, Cynthia Berlinicke, William Roush, Thomas Bannister, Zhiyong Yang, Donald Zack

Keywords(s): CNS and Neurological Disorders, Disease Indication, Eye Disorders, Glaucoma, Optic Nerve Diseases, Optic Neuropathy, Therapeutic Matter, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Ophthalmology > Glaucoma, Clinical and Disease Specializations > Ophthalmology > Optic Neuropathy, Technology Classifications > Therapeutic Modalities, Clinical and Disease Specializations > Ophthalmology

A Neuroprotective Agent with Applicability to Glaucoma, Optic Nerve Diseases, and other Neurodegenerations

C10454: Known Drug found to have applicability in the area of glaucoma, optic nerve diseases, and other neurodegenerationsValue Proposition: Key Features • Provides treatment for glaucoma, other optic nerve diseases, and potentially any disease with neuronal dysfunction or loss. • Exploits an FDA approved drug, which may reduce clinical hurdles and...

Published: 6/27/2024 | Inventor(s): Zhiyong Yang, Cynthia Berlinicke, Harry Quigley, Donald Zack

Keywords(s): Agonists/Promoters, CNS and Neurological Disorders, Disease Indication, Eye Disorders, Glaucoma, Non-novel, Optic Nerve Diseases, Optic Neuropathy, Predicted Novelty, Repurposed, Small Molecules, Therapeutic Matter, Therapeutic Substance, Therapeutics

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Ophthalmology > Glaucoma, Clinical and Disease Specializations > Ophthalmology > Optic Neuropathy, Technology Classifications > Therapeutic Modalities > Small Molecules, Clinical and Disease Specializations > Ophthalmology, Technology Classifications > Therapeutic Modalities