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Functional Analysis of Non-amplified/overexpressed HER2 L869R Heterozygous in Human Somatic Breast Cells

TITLE Functional analysis of non-amplified/overexpressed HER2 L869R heterozygous in human somatic breast cellsJHU Ref. #C13782ABSTRACTHuman epidermal growth factor receptor 2 (HER2) missense mutations have been reported in human cancers and primarily occur in the absence of HER2 gene amplification. Whether...

Published: 3/13/2025 | Inventor(s): Ben Ho Park, Daniel Zabransky, Sarah Croessmann

Keywords(s): Breast Cancer, Cancers, Cell Lines, Discovery/Research Tools, Disease Indication, Human Cell Lines, In Vitro Research Tool, Translational Research Biomarker

Category(s): Clinical and Disease Specializations, Clinical and Disease Specializations > Oncology > Breast Cancer, Clinical and Disease Specializations > Women's Health, Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Human Cell Lines, Clinical and Disease Specializations > Oncology, Technology Classifications > Research Tools