Search Results - garry+cutting

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Polymer-Nucleic Acid Nanoparticles for Gene Editing

Inventors: Jordan J. Green, Stephany Yi Tzeng, Garry R. Cutting, Erin W. Kavanagh Unmet NeedCystic fibrosis (CF) is a progressive, genetic disease that affects the lungs, pancreas, and other organs. There are close to 40,000 children and adults living with cystic fibrosis in the United States (see CFF). In people with CF, mutations in the cystic fibrosis...

Published: 3/14/2025 | Inventor(s): Jordan Green, Stephany Tzeng, Garry Cutting, Erin Kavanagh

Keywords(s):

Category(s): Clinical and Disease Specializations > Fibrosis, Technology Classifications > Therapeutic Modalities > Gene Therapies

Redesigned Potentiometric Wearable Sweat Sensor

Unmet NeedMore than 70,000 people worldwide live with cystic fibrosis (CF) and approximately 1,000 new cases of CF arise every year. Though most people are diagnosed with CF by the age of 2, some people are diagnosed as adults. Adult diagnoses are usually difficult because they are confirmed by a sweat chloride test which is not a standard test that...

Published: 3/14/2025 | Inventor(s): Peter Searson, Dong-Hoon Choi, Garry Cutting

Keywords(s):

Category(s): Clinical and Disease Specializations > Genetic Diseases > Cystic Fibrosis, Technology Classifications > Computers, Electronics & Software > Sensors

A potentiometric wearable sweat sensor

Unmet Need:The current method for measurement of chloride ion concentration in sweat in CF patients involves a visit to a clinic to collect a relatively large volume of sweat that can be analyzed by a conventional electrochemical reference electrode. In this invention, we describe a wearable sensor to reliably measure the concentration of chloride...

Published: 3/13/2025 | Inventor(s): Peter Searson, Garry Cutting, Dong-Hoon Choi

Keywords(s): Environmental Sensing, Imaging and Sensing Systems, Sensors

Category(s): Technology Classifications > Computers, Electronics & Software > Sensors, Technology Classifications > Industrial Tech > Energy, Infrastructure & Environment, Technology Classifications > Computers, Electronics & Software, Technology Classifications > Industrial Tech, Technology Classifications > Engineering Tech > Energy, Infrastructure & Environment

CF8Flp: A Cystic Fibrosis Bronchial Epithelial Cell Line with a Single Integration Site for the Stable Expression of any Gene of Interest

A Cystic Fibrosis Bronchial Epithelial Cell Line (CF8Flp)JHU REF: C12966Invention Novelty: The invention is in the form of a Cystic Fibrosis Bronchial Epithelial Cell Line with an integration site that allows for stable expression of the target protein.Value Proposition:Bronchial epithelial cells have been particularly instrumental in providing a means...

Published: 3/13/2025 | Inventor(s): Garry Cutting

Keywords(s): Basic Research Biomarker, Cell Model, Cloning Reagents, Cystic Fibrosis (CF), Discovery/Research Tools, Disease Indication, Epithelial Cells, Genetic Disorders, In Vitro Research Tool, Plasmid, Research Reagent

Category(s): Technology Classifications > Research Tools > Cell Lines, Technology Classifications > Research Tools > Vectors & Plasmids, Technology Classifications > Research Tools, Clinical and Disease Specializations > Genetic Diseases > Cystic Fibrosis